Although Hox genes
may function upstream of Pitxl, Six1 and Nkx3-1 after Gen treatment, the converse may also be true.
In the embryo's first moments, the Hox genes
are dormant, packaged like a spool of wound yarn on the DNA.
Crustacean appendage evolution associated with changes in Hox gene
, then, allow for context-sensitive operations.
TABLE 1: HOX gene
expression levels in lungs after MSCs administration.
Only a few Hox genes
have been found, one to two anterior genes, one to two central class genes, and a posterior class gene (Cook et al., 2004; Baguna et al., 2008b; Hejnol and Martindale, 2008).
Davidson et al., (1995) proposed that recruitment of Hox genes
to pattern regional specification along the anterior-posterior axis was an innovation that accompanied evolution of bilaterians.
Leckman of Yale University School of Medicine calls the new finding about the Hoxb8 gene "very exciting." Leckman's group is currently investigating possible effects of other Hox genes
Other recent work has shown that Hox gene
expression begins as early as stage L2 in the putative growth zone (Irvine, 1998; Irvine and Martindale, 1999b; Kevin J.
Conserved anterior boundaries of Hox gene
expression in the central nervous system of the leech Helobdella.
MLL targets SET domain methyltransferase activity to Hox gene
Reichert, "Functional equivalence of Hox gene
products in the specification of the tritocerebrum during embryonic brain development of Drosophila," Development, vol.