hormone-sensitive lipase

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hormone-sensitive lipase

an enzyme that catalyzes the release of fatty acids from adipose tissues.

hormone-sensitive lipase

enzyme responsible for hydrolysis of triglyceride molecules and therefore release of free fatty acids and glycerol. It functions mainly in adipose tissue and muscle. Activity of the enzyme in both sites is increased during endurance-type exercise, providing free fatty acids for resynthesis of ATP.
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Fatty acid synthase, hormone sensitive lipase, lipoprotein lipase, adipose triacylglycerol lipase, acyl-CoA, diacylglycerol acyltransferase 2, elongase of very long-chain fatty acid 6, and [DELTA]5 and [DELTA]6 fatty acid desaturase activity was detected and showed a negative trend with an increase of salinity, and no significant differences were found among salinity groups (P > 0.
In addition, enhancement of insulin secretion also inhibits hormone sensitive lipase and increases the utilization of glucose and thereby decreasing the mobilization of FFAs from the fat depots.
2) Also, the higher concentration of insulin in HHS as compared to DKA, may be sufficient to inhibit the action of hormone sensitive lipase, thus thwarting triglyceride breakdown to ketones in adipose tissue.
The increased lipolysis was accompanied by an increase in the expression of hormone sensitive lipase (1.

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