Furthermore, mtROS produced through RET appears to have particular relevance to hormetic
adaptation, including increased lifespan .
Zou et al., "Hormetic
effect of berberine attenuates the anticancer activity of chemotherapeutic agents," PLoS One, vol.
The exposure-response relationship was hormetic
, indicating that reducing radon in the home could in some cases increase lung cancer risk, especially for smokers.
Lu et al., "The germicidal and hormetic
effects of UV-C light on reducing brown rot disease and yeast microflora of peaches," Crop Protection, vol.
Midazolam causes a hormetic
Braun dose-response relationship in  human neuroblastoma cells.
Free radicals produced during exercise provoke a "hormetic
" adaptive response to physical activity that is highly muscle fiber-specific and also positively modulate several physiological functions, such as cell signaling, immune response, and apoptosis [2, 3].
Although numerous health benefits are associated with the consumption of phytochemicals, caution is needed when selecting an exploratory dose because of their hormetic
While I realize that the above quote suggests that animal protein is "bad" and vegetable protein is "good," I would hypothesize, as I have suggested, that this is not an issue of all or none but a hormetic
issue where dosage is the key determinant.
Methods: We examined the impact of both natural compounds, at concentrations in its hormetic
range on the following cell parameters: chymotrypsin-like activity of the proteasome system; PARP-1 protein levels and expression and caspase activation: APP processing; and the main endogenous antioxidant enzymes.
The dose-response curve of chemicals with a hormetic
effect looks like this:
It means that low concentrations of lead elevated the cell survival rate over the level of intact cells, which can be regarded as a hormetic
Thus, we propose that anoxic conditioning helps to reduce irradiation damage through a hormetic