homovanillic acid

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ho·mo·va·nil·lic ac·id (HVA),

(hō'mō-vă-nil'ik as'id),
4-Hydroxy-3-methoxyphenylacetic acid; a phenol found in human urine; produced through the methylation of homoprotocatechuic acid on the meta-OH group. It is the principal urinary metabolite of dopa and dopamine.

homovanillic acid

/ho·mo·va·nil·lic ac·id/ (ho″mo-vah-nil´ik) a major terminal urinary metabolite, converted from dopa, dopamine, and norepinephrine.

homovanillic acid (HVA)

[hō′mōvənil′ik]
an acid that is produced by the normal metabolism of dopamine and that may occur at an elevated level in urine in association with tumors of the adrenal gland. Its normal accumulation in a 24-hour collection urine sample is 15 mg.

homovanillic acid

HVA Physiology A major dopamine metabolite used to synthesize epinephrine and norepinephrine and excreted in urine; HVA is usually measured with the major catecholamines and other catecholamine metabolites; HVA is ↑ in neuroblastoma and ganglioneuroma Ref range 0-15 mg/24 hr urine. See Hypertension, Pheochromocytoma.

ho·mo·va·nil·lic ac·id

(HVA) (hō'mō-vă-nil'ik as'id)
A phenol found in human urine; produced through the methylation of homoprotocatechuic acid on the meta-OH group.

ho·mo·va·nil·lic ac·id

(HVA) (hō'mō-vă-nil'ik as'id)
A phenol found in human urine.

homovanillic acid (hō´mōvənil´ik),

n an acid that is produced by normal metabolism of dopamine and may be elevated in the urine in association with tumors of the adrenal gland.
References in periodicals archive ?
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride (MPTP-HCI, CAS Number: 23007854), Dopamine Hydrochloride (DA-HCI, CAS Number: 62-31-7), and Homovanillic Acid (HVA, CAS Number: 306-08-1) were purchased from Sigma-Aldrich (U.
Three years of experience with random urinary homovanillic and vanillymandelic acid levels in the diagnosis of neuroblastoma.
Metoclopramide induces catalepsy and increases striatal homovanillic acid content in mice.
homovanillic acid [HVA]) and increases in a metabolite of serotonin (i.
Those three patients had elevated homovanillic acid levels consistent with those seen in schizophrenia (Arch.
Homovanillic Acid (HVA) -- Urinary HVA is the end metabolite of catecholamines, dopamine and urinary vanillylmandelic acid (VMA).
Then, they allowed the hydrogen peroxide to react with homovanillic acid to form a fluorescent compound.
Dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), nor-adrenaline (NA), 5-hydroxy tryptamine (5-FIT), 5-hydroxyindole acetic acid (5-HIAA), dihy-droxybenzylamine (DHBA), epinephrine, t-butyl hydroperoxide, reduced glutathione (GSH), glutathione reductase, thiobarbituric acid, 1,3,3-tetraethoxypropane and 5, 5'-dithiobis (2-nitrobenzoic acid) (DTNB), standardized Panax quinquefolium (PQ) crude root powder [Rg: 0.
Plasma levels of homovanillic acid, 5-hydroxyindoleacetic acid and cortisol, and serotonin turnover in depressed patients.
5 mg Mn/kg body weight; range, 152-174 mg Mn/kg body weight) on DAT or D2R receptor levels using autoradiography or tyrosine hydroxylase immunohistochemistry, or on the concentration of dopamine and its metabolite homovanillic acid (HVA) measured by HPLC with electrochemical detection in the caudate or putamen, relative to naive controls (Guilarte et al.
Additional support for the utility of the ERG for subgrouping cocaine addicts with increased dopamine disturbances come from a recent study by Roy and colleagues (2003), in which concentrations of the dopamine metabolite homovanillic correlated with ERG blue cone b wave amplitude.
Homovanillic acid and 5-hydroxyindoleacetic acid cerebrospinal fluid levels.