homoserine lactone


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ho·mo·ser·ine lac·tone

the cyclic ester (that is, the δ-lactone) of homoserine; formed by the reaction of cyanogen bromide on methionyl residues in peptides and proteins.

homoserine lactone

(hō″mō-sĕr′ēn lăk′tō″n)
A signaling chemical used by gram-negative bacteria in quorum sensing.
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References in periodicals archive ?
To date, the best known communication between bacteria occurs via the N-acyl homoserine lactone (AHL): The enzyme Luxl produces signals that are recognised by the LuxR receptor, at which point the bacteria develop certain properties and modulate their behaviour towards one another.
In Gram negative bacteria, the QS mediated pathogenesis occurs through N-acyl homoserine lactone (AHL) signal dependent mechanism (Smith and Iglewski 2003).
For example, red algae secrete halogenated furanones and enones that act as antagonists of acylated homoserine lactone signaling molecules present in biofilms.
A receptor protein from the LuxR family of transcriptional regulators, upon binding an acylated homoserine lactone compound, interacts with the lux box, modulating the activity of the promoter.
Addition of homoserine lactone to the medium containing the mutant biofilms resulted in biofilms similar to the wild type with respect to structure and thickness.
Plants secrete substances that mimic bacterial N-acyl homoserine lactone signal activities and affect population density-dependent behaviors in associated bacteria.
Instead, the bacteria conserve their resources by making other chemicals, called acylated homoserine lactones, or AHLs, which cost much less energy to produce, Hmelo said.
Among the most common chemical "words" in the marine environment are modified amino acids called acylated homoserine lactones, or AHLs.
In Gram negative bacteria, the main signaling molecules are acyl homoserine lactones.
40) demonstrated the role of acyl homoserine lactones (HSL) in biofilms of P.