homing receptor


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homing receptor

An adhesion molecule on leukocytes that binds to endothelial cells in blood vessels. It is used by white blood cells to guide them to inflamed or infected tissues in the body.
See also: receptor
References in periodicals archive ?
Prognostic value of lymphocyte homing receptor and S phase fraction in non-Hodgkin's lymphoma.
The clinical efficacy of anti-TNF-[alpha] drugs in patients with psoriasis and/or joint disease was associated with (i) reduction of IL-6 and IL-22 in sera; (ii) increments of regulatory T cells; (iii) reduction of cutaneous homing receptor expressing T cells.
In addition, we are investigating ways to attach homing receptors to these nurse cells in order to help direct NK cells to where they need to go, whether it's the lymph nodes, brain tissue, bone marrow or other areas.
To address this hurdle, researchers at Brigham and Women's Hospital (BWH) have developed a platform approach to chemically incorporate homing receptors onto the surface of cells.