Holliday junction

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Hol·li·day junc·tion

(hol'ĭ-dā),

the cross-strand structure formed when two DNA duplexes cross in a recombination event.

Synonym(s): Holliday structure

[R. Holliday]

Farlex Partner Medical Dictionary © Farlex 2012

A cruciform structure formed as an intermediate in homologous genetic recombination

Holliday,

R.,

Holliday junction - the cross-strand structure formed when two DNA duplexes cross in a recombination event. Synonym(s): Holliday structure

Holliday structure - Synonym(s): Holliday junction

Medical Eponyms © Farlex 2012

Mentioned in ?

Holliday, R.

References in periodicals archive ?

Allele-specific Holliday junction formation-a new mechanism of allelic discrimination for SNP scoring.

Detecting the C282Y and H63D mutations of the HFE gene by Holliday junction-based allele-specific genotyping methods

Scientists have evidence that when chromosomes exchange genes, four strands from two DNA double helixes come together to form an intermediate structure called a Holliday junction, which looks like the street curbs of a four-way intersection.

DNA doubles in a four-stranded huddle

Some chapter topics include imaging and molecular motors, signal transduction across the plasma membrane, single-molecule tracking of quantum dot liganded epidermal growth factor, single- molecule FRET studies of helicases and Holliday junctions, and high- speed atomic force microscopy for nano-visualization of biomolecular processes.