Hogness box

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A highly conserved DNA sequence of about 180 base pairs near the 3' end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene expression in development.
Synonym(s): homeodomain
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Hogness box

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005


D.S., U.S. molecular biologist, 1925–.
Grunstein-Hogness assay - a procedure for identifying plasmid clones by colony hybridization.
Hogness box
Medical Eponyms © Farlex 2012