fusion inhibitor

(redirected from Hiv fusion inhibitors)
Also found in: Dictionary.

fusion inhibitor

a drug that prevents sufficient joining of viral and host cell membranes for infection to occur.

fusion inhibitor

n.
Any of a class of drugs that interfere with the entry of HIV into helper T cells by inhibiting the fusion of the viral and cell membranes.
References in periodicals archive ?
9 /PRNewswire-FirstCall/ -- New data presented in an oral session at the 13th Conference on Retroviruses and Opportunistic Infections (CROI) this week support the continued development of two next-generation HIV fusion inhibitor peptide candidates, Roche and Trimeris, Inc.
Panacos scientists have extensive experience in fusion inhibitor discovery, having previously played major roles in the discovery of protein and peptide-based HIV fusion inhibitors that provide proof of concept for this approach.
Panacos is currently collaborating with the National Cancer Institute (NCI) to identify novel HIV fusion inhibitors by screening the NCI's natural product repository using the Company's proprietary drug screening technology.
In addition to constituting a potential new class of HIV fusion inhibitors, the sulfated CCR5 peptides may provide a tool for identifying small-molecule drugs that target CCR5.
Finally, an update on Panacos' HIV fusion inhibitor program was provided in "Discovery of a Novel Class of Orally Bioavailable HIV-1 Fusion Inhibitors," an oral poster discussion presented by Dr.