HDAC1

(redirected from Histone deacetylase 1)
Also found in: Acronyms.

HDAC1

A gene on chromosome 1p34 that encodes histone deacetylase 1, which belongs to the histone deacetylase/acuc/apha family and is a part of the histone deacetylase complex. It interacts with retinoblastoma tumour-suppressor protein and controls cell proliferation and differentiation. With metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
References in periodicals archive ?
The report provides comprehensive information on the Histone Deacetylase 1 (EC 3.5.1.98), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
* The report provides a snapshot of the global therapeutic landscape for Histone Deacetylase 1 (EC 3.5.1.98)
* The report reviews Histone Deacetylase 1 (EC 3.5.1.98) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Protein BRCA1 Breast cancer 1, early onset HDAC1 Histone deacetylase 1 PLK1 Polo-like kinase 1 PML Promyelocytic leukemia CDKN2A Cyclin-dependent kinase inhibitor 2A SMAD1 SMAD family member 1 WT1 Wilms tumor 1 RB1 Retinoblastoma 1 YY1 YY1 transcription factor

Full browser ?