histiocyte

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histiocyte

 [his´te-o-sīt″]
macrophage. adj., adj histiocyt´ic.

his·ti·o·cyte

(his'tē-ō-sīt'),
A tissue macrophage; the class includes hepatic Kupffer cells, alveolar macrophages, giant cells of granulomas, osteoclasts, and dermal Langerhans cells. These cells derive from precursors that normally reside in bone marrow but migrate through the bloodstream to egress into tissues for final differentiation.
Synonym(s): histocyte
[histio- + G. kytos, cell]

histiocyte

/his·tio·cyte/ (his´te-o-sīt″) macrophage.histiocyt´ic

histiocyte

(hĭs′tē-ə-sīt′)
n.
A macrophage or dendritic cell that is usually immobile and is found in organs and tissues.

his′ti·o·cyt′ic (-sĭt′ĭk) adj.

histiocyte

macrophage

A nonspecific immune defence cell that interacts with proteins and polysaccharide antigens, internalising and partially degrading them, and/or presenting the antigens to T cells in a major histocompatibility complex (MHC) context. Macrophages are involved in secretion, immune interaction with T and B cells and provide lymphokine receptors; once activated, macrophages are highly microbicidal and tumouricidal, often closely associated with the blood vessels, epithelium and mesothelium, which are appropriate sites for non-specific immunocytes.
 
Morphology
Large (15–80 µm in diameter), often with bleb-like or filiform pseudopodia; one (or rarely more) round to oval, occasionally indented nucleus; nuclear membrane is distinct; nuclear chromatin is fine with a reticular pattern; abundant, pale grey-blue, often granulated (coarse azurophilic granules) and vacuolated cytoplasm with phagocytosed material (RBCs, WBCs, platelets, nuclei, bacteria and remnants in native or degraded form).

his·ti·o·cyte

(his'tē-ō-sīt)
A macrophage present in connective tissue.
Synonym(s): histocyte.
[histio- + G. kytos, cell]

histiocyte

A fixed scavenging cell (phagocyte) found in connective tissue. Histiocytes are also known as reticuloendothelial cells and reticulum cells. A macrophage that does not migrate.

histiocyte

macrophage present in connective tissue

his·ti·o·cyte

(his'tē-ō-sīt)
A macrophage in connective tissue.
[histio- + G. kytos, cell]

histiocyte (his´tēəsīt´),

n a large phagocytic cell found in the interstices of the tissues; of reticuloendothelial origin.

histiocyte

a large phagocytic interstitial cell of the reticuloendothelial system; a macrophage.
References in periodicals archive ?
31) Malakoplakia is characterized by a distinctive and potentially tumefactive infiltrate of histiocytes with abundant granular pink cytoplasm (von Hansemann histiocytes) that resemble the histiocytes of CSH.
Our unexpected discovery of viral production in placental, maternal, and fetal histiocytes is another example of transplacental passage of influenza.
Fortunately, two recent retrieval studies involving mechanically loose ceramic-on-ceramic bearings revealed that periprosthetic tissue changes in response to ceramic wear exhibited multiple histiocytes and tissue fibrosis, (40) with little to no plasma cells or lymphocytes, (41) suggesting a similar soft-tissue immune reaction as seen with metal-on-polyethylene wear.
14) Inflammatory pseudotumors consist of especially inflammatory cells like mature lymphocytes, plasma cells and histiocytes.
The confirmatory finding was electron microscopy of a biopsy, which showed oval electron-dense bodies within dermal histiocytes without any clearly identifiable melanin granules.
Pathologic findings of granuloma, fibrosis, and histiocytes suggest a local foreign-body-type reaction to metallic mercury.
LANGERHANS Cell Histiocytosis is caused by the abnormal behaviour of cells found throughout the body called histiocytes.
Erdheim-Chester disease (ECD) is a rare histiocytic disease involving the excessive production of histiocytes, a type of white blood cell.
3,7] Today it is reported that the cells that MFHs originate from fibroblasts or undifferentiated mesenchymal cells; the available histiocytes are reactive and using the term fibrohistiocytic would be definitive as well.
Taylor described meconium histiocytes as "almost universal" in the sickle cell carriers' placentas.