Winkler, Hill's Equation
, Inderscience Publishers, New York, NY, USA, 1966.
This model also does not follow Hill's equation that describes the substrateenzyme interaction that has multiple ligand-binding sites.
We assume that the interactions of the protein follow the Michaelis Menten and Hill's equation. The mutation of the growth regulatory genes such as FLT3-ITD is common in AML cases and results in the activation of PI3K .
According to the fact that AKT has two binding sites, this protein activity is assumed to follow Hill's equation with coefficient 2.
2.2 is of particular interest, in fact, it improves the classical Lyapunov's inequality not only for the Hill's equation
, but also the Sturm-Liouville equation satisfying (1.2) for [beta] = [gamma] = 1.
For measurements made at pH 10.0 and 11.0, the velocities were fitted by nonlinear regression to Hill's equation of the form:
Better fit was obtained with Hill's equation (see supplementary Table 1 for details).
Then the roots of the characteristic equation corresponding to Hill's equation
With this law of variation the equations of motion reduce to Hill's equation
with periodic coefficients which has been solved by the method given by Valeev (1960).
For large random mating populations, only two of the six covariances, [[Sigma].sub.mm,mf] and [[Sigma].sub.fm,ff], are relevant and Hill's equation
is correct and also has a wide generality.
Throughout this paper, we assume that the equation, known as Hill's equation
The aim of this paper is to employ a series of assumptions that simplify Hill's equation
and yet allow sex differences to be incorporated.