Our genomic imprinting study focused on highly conserved sequence
characteristics in the set of particular species being studied.
These reagents contain shorter highly conserved sequence
regions improving assay specificity, and the probes are non-cleavable which allows post-PCR melt curve analysis.
Hammerhead ribozymes, as based on the Haseloff and Gerlach model (Nature, 1988), consist of a catalytic core made up of a highly conserved sequence
of 24 nucleotides that cleave substrate RNAs.
The slow-evolving SSU rRNA is often the best marker for molecular phylogenetic analysis as it is ubiquitous with multiple copies highly conserved sequence
and has exactly the same function in all cells.
By the advent of molecular technologies based on Polymerase Chain Reaction (PCR) for the ribosomal gene amplification is used for the genetic identification of many organisms because they comprise both highly conserved sequences
during evolution and highly variable sequences among species.