Immediately following the second HKD motif and in the middle of the highly conserved sequence
IGSANINQR, there is an invariant serine residue.
In the present study, we have also observed the presence of highly conserved sequence
"DG" towards its C-terminus.
Our genomic imprinting study focused on highly conserved sequence
characteristics in the set of particular species being studied.
These reagents contain shorter highly conserved sequence
regions improving assay specificity, and the probes are non-cleavable which allows post-PCR melt curve analysis.
Hammerhead ribozymes, as based on the Haseloff and Gerlach model (Nature, 1988), consist of a catalytic core made up of a highly conserved sequence
of 24 nucleotides that cleave substrate RNAs.
The slow-evolving SSU rRNA is often the best marker for molecular phylogenetic analysis as it is ubiquitous with multiple copies highly conserved sequence
and has exactly the same function in all cells.