Hib-MenCY-TT is safe and immunogenic against
Hib and N.
Yapilan calismalar da gostermektedir ki, asilamanin invaziv
Hib enfeksiyonlarini onlemedeki basarisi aciktir.
Anne Schuchat, director of the CDC's National Center for Immunization and Respiratory Diseases, stressed the "critical importance" of reinstating the booster dose of
Hib vaccine in children aged 12-15 months, in a July 30 letter to health care providers.
Another development likely to ease the burden of programme managers is the shift from freeze-dried
Hib vaccine (which has to be reconstituted before administration) to fully liquid
Hib vaccine.
The names of children 2-4 years of age with full
Hib vaccination (3 doses) were obtained from district computerized immunization records.
Ongoing studies suggest, for example, that even among those who respond to the current vaccine, there may be a "window' of increased susceptibility to
Hib infection during the first seven days after immunization.
At this time, production of Merck
Hib vaccine products remains suspended; however, supplies of Sanofi Pasteur vaccines ActHIB (monovalent
Hib vaccine) and Pentacel (DTaPIPV/
Hib) are available for use for the primary
Hib vaccination series and booster in infants and children.
The
Hib vaccine shortage does not appear to have resulted in an increase in the number of disease cases in children less than 5 years of age, said the CDC's Dr.
Asilanmamis dort yas altindaki (evde veya kreste yasayan) cocuklar disinda asplenik, sickle cel anemili, HIV'li, diger immun yetmezlikli, malign neoplazmali gibi ozel durumlardaki cocuklar da invazif
Hib enfeksiyonu icin riskli hastalardir.
The major obstacles to introducing
Hib conjugate vaccines into developing countries have been their cost and the population's limited awareness about the impact of
Hib disease.
Hib was first given as a single vaccine in 1992 as part of a national campaign and is now given with DTwP, diphtheria, tetanus and pertussis, or whooping cough, at two, three and four months.
From 1998 to 2000, rates of invasive
Hib disease among children less than 5 years of age ranged from 0 to 2.
