Heyde syndrome

Heyde syn·drome

(hād sin'drōm)
A gastrointestinal disorder involving hemorrhage and anemia secondary to aortic valve stenosis. These symptoms resolve after repair or replacement of the damaged aortic valve.


Edward C., U.S. physician.
Heyde syndrome - occurrence of gastrointestinal bleeding and aortic stenosis after replacement of aortic valve.
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References in periodicals archive ?
Particular types of angiodysplasia include the Heyde syndrome, which consists of the association of angiodysplasia with aortic valve stenosis, in the presence of type II A of the von Willebrand disease (Khan & Massyn 2009; Pate et al 2004; Maor Roguin 2013).
Also, Heyde syndrome is characterized by calcific aortic stenosis, acquired von Willebrand disease, and angiodysplasia in colon and caecum causing gastrointestinal haemorrhage.
A female patient with Heyde Syndrome, in which gastrointestinal (GIS) bleeding is common due to GIS angiodysplasia, had Edwards SAPIEN valve placed and thus, both the aortic stenosis and GIS bleedings were treated by this intervention.
The characterization of Heyde syndrome now refers to the triad of AS, acquired coagulopathy (von Willebrand syndrome type 2A, or vWS-2A) and anemia due to bleeding from intestinal angiodysplasia.
Therefore, the prevalence of Heyde syndrome is not clearly determined and many mild cases are likely to remain undiagnosed.