Heubner-Herter disease

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Heubner-Herter disease

 [hoib´ner her´ter]
celiac disease of infants.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

coeliac disease

A malabsorptive syndrome caused by hypersensitivity of intestinal mucosa to alpha-gliadin, a gluten extract composed of glutamine and proline-rich proteins that is found in wheat, barley, rye, and oats.
Clinical findings
Diarrhoea, copious fatty stools, abdominal distension, weight loss, haemorrhage, osteopenia, muscle atrophy, peripheral neuropathy, CNS and spinal cord demyelination (sensory loss, ataxia), amenorrhoea, infertility, oedema, petechiae, dermatitis herpetiformis (especially if HLA B27), alopecia areata. Occult bleeding occurs in half of patients.
Transaminases (ALT, AST) are increased in ± 40% of patients with CD, which usually normalises with a gluten-free diet; iron deficiency, anaemia due to occult bleeding.

Duodenal biopsy; anti-gliadin and anti-endomysial antibodies.
Eliminate gliadin from diet.

Without treatment, 10–15% develop lymphoma (e.g., immunoblastic lymphoma; less commonly, T cell lymphoma), a risk that increases with disease duration. CD predisposes to gastrointestinal lymphoma and carcinoma of the oral cavity and oesophagus; the otherwise rare small intestinal adenocarcinoma is 80-fold more common in CD.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Heubner, Johann Otto L.

German pediatrician, 1843–1926.

Heubner's disease

Syphilitic endarteritis of the brain.

Heubner-Herter disease

Nontropical sprue in infants.
Medical Dictionary, © 2009 Farlex and Partners


Christian A., U.S. physician, 1865-1910.
Gee-Herter disease - Synonym(s): Gee disease
Herter disease - gluten sensitivity, manifested by diarrhea, malabsorption, steatorrhea, nutritional and vitamin deficiencies. Synonym(s): celiac disease
Heubner-Herter disease - Synonym(s): Gee disease


Johann O.L., German pediatrician, 1843-1926.
artery of Heubner - a cerebral artery. Synonym(s): medial striate artery
Heubner arteritis - inflammation of arteries within the circle of Willis secondary to chronic basal meningitis from tubercle bacillus or particular fungi.
Heubner-Herter disease - Synonym(s): Gee disease
Medical Eponyms © Farlex 2012