dimer

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Related to Heterodimers: Homodimer, Homodimeric, Heterodimeric

dimer

 
1. a compound formed by combination of two identical simpler molecules.
2. a capsomer having two structural subunits.
D-dimer a fragment of fibrin that is formed as a result of fibrin degradation. A positive test for its presence in the blood is suggestive of conditions such as thrombotic disease, sickle cell crisis, malignancy, disseminated intravascular coagulation, or recent surgery.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

di·mer

(dī'mĕr),
A compound or unit produced by the combination of two like molecules; in the strictest sense, this occurs without the loss of atoms (thus, nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (for example, a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]
Farlex Partner Medical Dictionary © Farlex 2012

di·mer

(dī'mĕr)
A compound or unit produced by the combination of two like molecules; in the strictest sense, without loss of atoms (thus nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (e.g., a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

dimer

a molecule made by the joining of two molecules of the same kind, i.e. two MONOMERS. Ultraviolet light can induce THYMINE DIMERS in DNA.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
In keeping with previous reports, these results lead us to consider that recruitment of [gamma]c to IL-7/IL-7R[alpha] which occurs in sequential dimerization model would be impossible in 4[degrees]C and sodium azide medium, suggesting that the epitope masking may result from conformational changes of surface [gamma]c protein with preassembled heterodimer model [12, 13, 19].
Funayama et al., "Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks," Nucleic Acids Research, vol.
Lobaccaro et al., "Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers," Science, vol.
In particular, once LXRs form a heterodimer with RXR, they stimulate the transcription of an array of genes involved in the absorption, efflux, transport, and excretion of cholesterol and other lipids [21].
TAM67 forms heterodimers with other AP1 transcription factors and these complexes bind to DNA, but the complexes are not able to activate transcription [100,101].
Tarrade et al., "The role of PPAR-[gamma]/RXR- [alpha] heterodimers in the regulation of human trophoblast invasion," Annals of the New York Academy of Sciences, vol.
As already discussed above, the binding of CRMP2 to tubulin heterodimers can enhance microtubule assembly leading to axon outgrowth [123, 124].
Structural determinants of allosteric ligand activation in RXR heterodimers. Cell, 116: 417-429.
PPAR/retinoid X receptor (RXR) heterodimers bind to these response elements through the PPAR DNA binding domain, which is a highly conserved domain similar to various transcription factors (1), (2).
Research and development company for cancer drugs Eutropics Pharmaceuticals announced on Tuesday that the US Patent and Trademark Office has issued patent number 8,168,755 entitled, "Antibodies specific to heterodimers of Bcl-2 family and uses thereof".
The study further suggests that kappa-mu opioid receptor heterodimers could function as a molecular switch that shifts the action of kappa-opioid receptors and endogenous chemicals that act on them from pain promoting to pain alleviating.
HER2 has the strongest catalytic kinase activity and HER2-containing heterodimers have the strongest signaling activity.