dimer

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Related to Heterodimerization: Homodimer

dimer

 
1. a compound formed by combination of two identical simpler molecules.
2. a capsomer having two structural subunits.
D-dimer a fragment of fibrin that is formed as a result of fibrin degradation. A positive test for its presence in the blood is suggestive of conditions such as thrombotic disease, sickle cell crisis, malignancy, disseminated intravascular coagulation, or recent surgery.

di·mer

(dī'mĕr),
A compound or unit produced by the combination of two like molecules; in the strictest sense, this occurs without the loss of atoms (thus, nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (for example, a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

dimer

/di·mer/ (di´mer)
1. a compound formed by combination of two identical molecules.
2. a capsomer having two structural subunits.

dimer

[dī′mər]
Etymology: Gk, di, twice, meros, parts
a compound formed by the union of two radicals or two molecules of a single simpler compound.

di·mer

(dī'mĕr)
A compound or unit produced by the combination of two like molecules; in the strictest sense, without loss of atoms (thus nitrogen tetroxide, N2O4, is the dimer of nitrogen dioxide, NO2), but usually by elimination of H2O or a similar small molecule between the two (e.g., a disaccharide), or by simple noncovalent association (as of two identical protein molecules); higher orders of complexity are called trimers, tetramers, oligomers, and polymers.
[G. di-, two, + -mer]

dimer

a molecule made by the joining of two molecules of the same kind, i.e. two MONOMERS. Ultraviolet light can induce THYMINE DIMERS in DNA.

dimer

chemical compound formed by the union of two identical molecules.
References in periodicals archive ?
Their binding to specific response elements requires heterodimerization with RXR (3), (12).
Another BR-HLH-LZ domain containing protein; Max is identified as a closely related, obligate and physiological heterodimerization partener of c-Myc (Blackwood and Eisenman, 1991).
Distinguishing between calpain heterodimerization and homodimerization.
Heterodimerization between erbB2 and erbB3 has been reported to preferentially induce the activation of the Akt pathway.
It could be also due to structural differences in sortilin 1 expressed by cancer cells leading to impaired heterodimerization with other co-receptors (p75NTR) which is necessary for signal transduction.
HER-2, however, can signal as a result of heterodimerization with other HER family members and appears to be the preferred heterodimerization partner (28).
The DBD associates with nuclear proteins at the thyroid response elements (TREs) in order to regulate TR gene activation or repression (Harvey and Williams, 2002) and heterodimerization strongly increases binding to the TRE and transcriptional activity (Ikeda et al.
This mechanism involves sequential actions of E2, P4, IFNT, CSH1 and GH1 with biological actions of CSH1 being mediated by homodimerization of the PRLR or heterodimerization of the PRLR and GH1 receptor (Noel et al.
The suggested molecular functions of N6AMT1 include protein heterodimerization and methionine S-methyltransferase activity, with an almost certain (100%) predicted probability of being a methyltransrerase.
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR.
13) It has no known ligand, and therefore is hypothesized to serve a regulatory role through its heterodimerization with other ErbB family members.
Ligand binding to this cytosolic receptor induces nuclear translocation (Gasiewicz and Bauman 1987) and heterodimerization with another bHLH/PAS protein, ARNT (AhR nuclear translocator) (Reyes et al.