heterodimer


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to heterodimer: Homodimer, Heterodimerize

het·er·o·di·mer

(het'ĕr-ō-dī'mĕr),
A molecule composed of paired proteins with some amino-acid sequence variations.
[hetero- + dimer]
References in periodicals archive ?
Importance of Celiac Disease Patients Lacking Hla Dq2 or Dq8 Heterodimer in Slovenia.
The active AhR then goes into the nucleus and binds with ARNT to form a heterodimer.
PPARs are members of the nuclear-receptor superfamily of proteins and act as nuclear transcription factors where they form a heterodimer with the Retinoid X Receptor (RXR).
Although C8[alpha] occurs as a disulfide-linked heterodimer with C8[gamma], it retains the ability to interact noncovalently with C8[gamma] after cleavage of the interchain disulfide bond.
The activated form of NF-[kappa]B is a heterodimer, generally, which consists of two proteins, a p50 subunit and a p65 subunit, playing the key role in various courses of transcription.
11) The TAP structure is formed of two proteins: TAP1 and TAP2, which assemble into a heterodimer.
It is a heterodimer composed of two subunits [alpha] and [beta], joined non-covalently.
We show that inhibition is not due to a direct modification of the active NF-kappaB heterodimer.
NF-E2 functions as a heterodimer with small Maf proteins that are ubiquitously expressed (17).
Convergence of 9-cis retinoic acid and peroxisome proliferator signaling pathways through heterodimer formation of their receptors.
More specifically, the present invention relates to three (3) antigens from WNV (the secreted envelope glycoprotein (E), the heterodimer glycoproteins (pre-M-E) and the NSI protein) and from Dengue virus (the secreted envelope glycoprotein (e), the heterodimer glycoproteins (pre- m-e) and the nsl protein) and their use in vaccinal, therapeutic and diagnostic applications.
Presentation of scientific data on the HER1 and HER3 total protein assays, the HER1:HER1 homodimer assay, the HER1:HER2 and HER2:HER3 heterodimer assays and the PI3K assay (at the 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Geneva, Switzerland in October 2008, at the AACR Targeting the PI3-Kinase Pathway in Cancer meeting in Cambridge, MA in November 2008, and at the San Antonio Breast Cancer Symposium in December, 2008).