Polygonum Multiflorum

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A perennial herb used in traditional Chinese medicine, the roots, stems, and leaves of which are used for anaemia, premature grey hair, colitis, constipation, infertility, insomnia, malaria, nocturnal emission, postpartum pain, rheumatic complaints, skin infections, spermatorrhea, vaginal discharge, vertigo; some data suggest that cornblind may be antibacterial
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Currently, Heshouwu remained to be controversial in terms of its safety and effects, and functions and role of Heshouwu are not entirely conclusive, due to absence of excluding confounding DILI causality factors (such as heavy metals, pesticides, and fungal toxin contamination) and lack of pharmacognostic identification of patients' digested materials.
For example, not as other well-known hepatotoxic herbs, the potential risk of Heshouwu was not fully clarified in the clinical community and therefore the hepatotoxic risk among herbs should be paid attention to in clinical practice and by regulatory administration [15].
Polygoni Multiflori Radix ((PMR), heshouwu in Chinese) and Polygoni Multiflori Radix Praeparata ((PMRP), zhiheshouwu in Chinese) are originated from the root of Polygonum multiflorum Thunb.
Tangshen (Codonopsis pilosula), Huangqi (Astragalus mongholicus), Gouqizi (medlar), Heshouwu (Polygonum multiflorum), Quanshen (bistort root), and Tengligen (Chinese Actinidia root) were purchased from Beijing Tongrentang Co.