SERPIND1(redirected from Heparin cofactor II)
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Related to Heparin cofactor II: heparin cofactor 2
SERPIND1A gene on chromosome 22q11.21 that encodes a member of the serine protease inhibitor (serpin) family that rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. SERPIND1 shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.
SERPIND1 mutations are associated with heparin cofactor-II deficiency.