illness cells/L 1 ([dagger]) GVHD, renal 110 failure 2 ([dagger]) None 540 3 GVHD 1,470 4 None 1,440 5 Renal failure 0 6 ([dagger]) CMV, GVHD 154 7 Lung metastasis, 366 thoracotomy, restrictive syndrome 8 None 1,145 * BMI, body mass index; HCT, hemopoietic cell
transplant; AML, acute myeloblastic leukemia; allo, allogenic; MMF, mycophenolate mofetil; GVHD, graft-versus-host disease; NA, not applicable; CML, chronic myeloblastic leukemia; TBI, total body irradiation; ALL, acute lymphoblastic leukemia; CSA, cyclosporine; CMV, cytomegalovirus; ATG, antithymocyte globuline.
Further immunological characterization of pathological cells in the clinical laboratory should be performed whenever a specific feature of these cells has been shown to be of clinical importance for the diagnosis (immunological features that are specific of a certain cell lineage and maturation stage), prognosis (subclassification of leukemias affecting the same hemopoietic cell
lineage according to differentiation features or phenotypic characteristics associated with certain genetic abnormalities), or monitoring of the disease (investigation of phenotypic aberrations and abnormal differentiation pathways).
To quantify hemopoietic cell
proliferation, tunicate tissue cultures were established by excising small portions (2 x 2 mm) of the pharynx for explant culture in tunicate tissue culture medium (T-RPMI; Raftos and Cooper, 1990).
cells representing the first line of defense in vivo against virus infections and developing neoplasms, but also on a wide range of other immune and hemopoietic cell
populations in the bone marrow and spleen of mice.
These findings indicate that the hemopoietic cell
cycle is still functional in p53-KO mice during benzene exposure, whereas in WT mice it is arrested because of alterations in the expression of cell-cycle checkpoint genes, particularly the p53 gene (Yoon et al.
MUC13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells
Studies have shown that this age related loss of marrow hemopoietic cells
and decline in thymic function is reversed by growth hormone.
Aplastic anemia which may be congenital or acquired, is the result of failure of normal hemopoietic cells
of the bone marrow which results in decreased production of all types of blood cells (RBCs,WBCs platelets).
2) consisting of hemopoietic cells
including polymorphs, myelocytes, metamyelocytes and occasional promyelocytes (Fig.
Unfortunately, at anti-inflammatory doses, some of these molecules showed genotoxicity (Williams and Grayer 2004) or were cytotoxic for normal human hemopoietic cells
(Ferry-Dumazet et al.
The remainder of the cell population, containing various types of non-adherent hemopoietic cells
, were removed on the fifth day of cultivation by replacing the existing medium with fresh medium.
give rise to the cells of the blood system.