Keywords: Hemimegalencephaly, Hemiparesis, Intractable epilepsy, Hemispherectomy
Cell culture and drug treatment: In this study we used HCN-2 cell line derived from the cortical tissue of the brain from the patients undergoing hemispherectomy
for intractable seizures.
MR imaging is more sensitive in detecting complications of hemispherectomy
, such as extra or intra-axial haemorrhage, hydrocephalus or infections.
is a palliative surgical approach that aims to control potentially harmful seizures, for instance, atonic or drop seizures, preventing the spread of epileptic electrical activity (1,2,3,18,27).
In the case of a pharmacoresistant epilepsy, a hemispherectomy
is a treatment of choice with a success rate of 85% in carefully selected cases.
An example of this is a functional hemispherectomy
, where the diseased hemisphere is disconnected from the rest of the brain and the patient does not have dangerous progression of focal seizures to generalised seizures.
Children with intractable disabling seizure and hemiplegia may benefit from hemispherectomy
It seems that when it comes to singing, the right hemisphere assumes the majority of responsibilities, especially when singing a familiar song; some patients whose left hemisphere had been removed completely through a hemispherectomy
could still sing familiar songs well.
RASMUSSEN'S SYNDROME AND HEMISPHERECTOMY
Given the severity of James' condition - the right hemisphere of the brain had shrunk and atrophied irrevocably from the seizure activity - the only fix was a hemispherectomy
to remove the damaged right half of the brain.
sup] reported that out of 124 patients with intractable epilepsy, there were 48 cases with extra-temporal lobe epilepsy, 45 subjects were treated with foci resection combined with electro-coagulation on functional cortex, three patients were treated with pure electro-coagulation on functional cortex, and only one case with infantile hemiplegia underwent functional hemispherectomy
combined with electro-coagulation of the remaining tissue.
For example, children with a hemispherectomy
have difficulty in adapting temporal parameters but not spatial parameters .