megalencephaly

(redirected from Hemimegalencephaly)

megalencephaly

 [meg″ah-len-sef´ah-le]
macrencephalia; hypertrophy of the brain.

megalencephaly

(mĕg′əl-ĕn′sĕf′ə-lē) or

megaloencephaly

(mĕg′ə-lō-ĕn-)
n.
Abnormal largeness of the brain.

meg′al·en′ce·phal′ic (-ĕn′sə-făl′ĭk), meg′al·en′ce·phal′ous (-əs) adj.

megalencephaly

A rare condition defined as a brain that weighs significantly more than the average for an infant’s age and sex, which is invariably accompanied by macrocephaly with an enlarged cranial vault due to separation of the cranial sutures.

megalencephaly

Neonatology Big-brained
References in periodicals archive ?
My husband, Bryan, 45, and I were so excited, but at 25 weeks Theo was diagnosed with hemimegalencephaly - a rare neurological condition in which one half of the brain is abnormally large and the other half doesn't develop.
My husband, Bryan, 45, and I were so excited, but at 25 weeks Theo was diagnosed with hemimegalencephaly -- a rare neurological condition in which one half of the brain is abnormally large and the other half doesn't develop.
Hemimegalencephaly, which is a rare neurological condition in which one-half of the brain or one side of the brain is abnormally larger than the other was noted in one patient.
Isolated Hemimegalencephaly (iHME) is a rare form of congenital malformation of cortical development.
So that, the use of hemispherectomy in unilateral focal process, like Rasmussen syndrome, Sturge-Weber sydrome, hemimegalencephaly, extensive vascular insults hemispherical and trauma cranioencephalics are likely to better control of the seizure when compared to diffuse or bilateral processes such as malformations of cortical development.
The CNS abnormalities include mental retardation, seizures, and hemimegalencephaly. (1) Therefore, a thorough neurologic and ophthalmologic examination should be performed in patients with suspected nevus sebaceous syndrome.
Mosaicism in the nervous system is associated with diseases including epilepsy, lissencephaly, hemimegalencephaly, early-onset Alzheimer disease, autism spectrum disorders, and others (Poduri et al.
This is the case of Tuberous Sclerosis Complex (TSC), hemimegalencephaly (HME), focal cortical dysplasia (FCD), Pretzel syndrome (Ps), and familial focal epilepsy with variable foci (FFEVF) [112-117].
focal) Epilepsies attributed to and organized by structural-metabolic causes Malformations of cortical development (hemimegalencephaly, heterotopies, etc.) Neurocutaneous syndromes (tuberous sclerosis complex, Sturge-Weber, etc.) Tumor Infection Trauma Angioma Perinatal insults Stroke Etc.
The differential diagnoses for RE include Dyke-DavidoffMasson syndrome, Sturge-Weber syndrome, hemimegalencephaly, and unihemispheric cerebral vasculitis.
Other features that can be associated with Klippel-Trenaunay-Weber syndrome are polydactyly [13], syndactyly, seizures and hemimegalencephaly [14], spina bifida, lymphatic obstruction, chronic venous insufficiency, limb ulceration, and thromboembolism [15].
London, June 25 ( ANI ): Experts say gene mutations are likely culprits for causing Hemimegalencephaly, a rare but dramatic condition in which the brain grows asymmetrically, with one hemisphere becoming massively enlarged.