IFIH1(redirected from Helicase with 2 CARD domains)
IFIH1A gene on chromosome 2q24.2 that encodes an RNA helicase which, through its ATP-dependent unwinding of RNA, may promote message degradation by specific RNases. It is thought to have roles in suppressing growth and involved in innate immune defence viruses.
Genetic variation in IFIH1 is associated with diabetes mellitus insulin-dependent type 19.
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