Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Idioms, Encyclopedia, Wikipedia.


Hans, German anatomist, 1866-1942. See: Held bundle, Held decussation.


A gene on chromosome 1p36.1-p35 that encodes AT-rich interactive domain-containing protein 1, which is highly expressed in the spleen, thymus, prostate, testes, ovaries, small intestine, colon and peripheral leukocytes. ARID1A is involved in transcriptional activation and repression of select genes by chromatin remodelling (by altering DNA-nucleosome topology). It is also involved in vitamin D-coupled transcription regulation by associating with the WINAC complex, a chromatin-remodelling complex recruited by vitamin D receptor.

ARID1A belongs to the neural progenitors-specific chromatin remodelling (npBAF) and the neuron-specific chromatin remodelling (nBAF) complexes, which are involved in switching developing neurons from stem/progenitors to post-mitotic chromatin remodelling as they exit the cell cycle and become committed to their adult state.

Molecular pathology
Defects in ARID1A cause mental retardation autosomal dominant type 14.
References in periodicals archive ?
A domestic corporation, A, forms a foreign corporation, E A, which is held by a group of individuals, subsequently transfers several foreign subsidiaries to F in exchange for F stock.
March 16--This year's highly anticipated 19th Annual Co-op & Condo Expo, which will include 220 booths, will be held at the New York Hilton, 1335 Avenue of the Americas.
3) Interests previously held by a financial holding company under limited authority.
3-1-00, rev'g and remd'g TC Memo 1998-167), an unpublished opinion, the court held that an estate could present evidence of the appropriate amount a hypothetical willing buyer and seller would consider as a discount or adjustment in valuing the stock, based on the built-in capital gains on the corporation's real estate.
Some commenters argued that the proposed capital charge will make it difficult for securities firms to become financial holding companies by requiring that, as soon as they acquire a bank, they meet higher regulatory capital requirements on the equity investments already held by the firm.
Olsen, the Supreme Court of Tennessee held that capital gains realized when a corporation liquidated four subsidiary corporations were nonbusiness income.
The proposed SOP recommends depreciation expense be recognized on depreciable foreclosed assets held for sale beginning no later than one year after foreclosure.
ceremony will be held at San Fernando Mission Cemetery, 11160 Stranwood Ave.
He most recently held the position of Principal Consultant with Quest Fusion International Consulting.
iii) Real property that does not give rise to rental of similar income, to the extent used or held for use in the controlled foreign corporation's trade or business; (iv) Intangible property (as defined in section 936(h)(3)(B)), goodwill of going concern value, to the extent used or held for use in the controlled foreign corporation's trade of business.
Should the banks' capital decline, the Board could take action to preserve the safety and soundness of the subsidiary insured depository institutions, including requiring divestiture by the parent holding company of shares already held.
The 4600r is a breakthrough 2D imager product, building on Hand Held Product's 5thgeneration imaging technology.