Heinz body


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Heinz body

A modicum of denatured haemoglobin found in an erythrocyte.

Aetiology
Haemolytic anaemia, NADPH deficiency, G6PD≠glucose-6-phosphate dehydrogenase deficiency exacerbated by oxidant drugs—e.g., primaquine, dapsone, quinidine, chronic liver disease, alpha thalassemia.

Heinz body

see Heinz body.
References in periodicals archive ?
Rana and Bhardwaj (1988) ruled out the possibility of Heinz bodies and involvement of compliment system activation in this disease after investigating cytomorphological changes in erythrocytes of haemoglobinuric buffaloes through scanning electron microscopy whereas; Heinz body formation in erythrocytes of haemoglobinuric animals have been reported by Elison et al.
This process helps in rendering the erythrocytes vulnerable to Heinz body formation as a result of feeding on cruciferous /toxic plants (Smith et al.
Previous reports indicate that Heinz body formation in erythrocytes of haemoglobinuric animals is associated with hypocoprosis.