Heinz bodies


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Related to Heinz bodies: basophilic stippling

Heinz bod·ies

(hīnz),
intracellular inclusions usually attached to the red blood cell membrane, composed of denatured hemoglobin; they occur in thalassemia, enzymopathies, hemoglobinopathies, and after splenectomy. Visualization of these usually requires examination of red blood cells using supravital stains or by phase microscopy.

Heinz bod·ies

(hīnz bodēz)
Intracellular inclusions usually attached to the red blood cell membrane, composed of dentured hemoglobin; they occur in thalassemia, enzymopathies, hemoglobinopathies, and after splenectomy. Visualization of these usually requires examination of red blood cells using supravital stains or by phase microscopy.

Heinz,

Robert, German pathologist, 1865-1924.
Heinz bodies - intracellular inclusions composed of denatured hemoglobin.
Heinz body anemia
Heinz body test - a test for glucose 6-phosphate dehydrogenase-deficient red blood cells.
Heinz-Ehrlich body - Synonym(s): Ehrlich inner body
References in periodicals archive ?
In the present study, hypocuprosis was not recorded in haemoglobinuric buffaloes which might be the reason for absence of Heinz bodies in erythrocytes of effected animals.
Levels of total sulphydryl content, nitrosothiol, glucose 6-phosphate dehydrogenase, glutathione peroxidase, superoxide dismutase and catalase in the RBC of liver cirrhotic patients and normal controls Parameters Normal controls (n=45) Total -SH content ([micro]g 21.6 [+ or -] 3.1 GSH/g Hb) Nitrosothiol (nM nitrite/mg Hb) 1.1 [+ or -] 0.20 Glucose 6- phosphate 0.936 [+ or -] 0.18 dehydrogenase (Unit/g Hb) Heinz bodies (No.
Table 2: Laboratory Findings in Hemolytic Anemia Parameter Findings in Hemolytic Anemia (Normal range) RBC Decreased (Males; 4.6 to 6.2 x [10.sup.6] cells/ [mm.sup.3] Females: 4.2 to 5.4 x [10.sup.6] cells/[mm.sup.3] Hb Decreased (11 to 12 g/dL) Hct Decreased (33% to 36%) MCV Unchanged (Males: 80 to 96 fL Females: 82 to 98 fL) MCH Unchanged (27 to 33 pg/cell) MCHC Unchanged (31 to 35 g/dL) Reticulocytes Increased (0.5% to 2.5% of RBCs) Antigoblin tests Positive (Negative) (in immune types) Serum haptoglobin Decreased (40 to 240 mg/dL) Plasma free Hb Increased (100 to 210 IU/L) Heinz bodies Present (Absent) Haptoglobin (Hb-binding protein) is frequently used to screen for the hemolysis.