Hedgehog Gene

Any of a family of genes critical in the structural development of organisms from the stage of fertilized egg to early embryo; HG products act in a gradient fashion, controlling the organization of the body shape and structures—e.g., limbs and digits, brain and spinal cord. Hedgehog genes encode hedgehog proteins
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The genetic change means the Sonic hedgehog gene, which also controls the development of many organs, flickers only briefly when the embryo is only 24 hours old and then goes out at the point when limbs develop.
If it turns out one of these genes is medically important, and they have to tell a patient - you have a mutation in your Sonic Hedgehog gene - it's a little difficult.
DISCUSSION: EMBRYOGENESIS: Notochord is not necessary for nephrogenesis but is required for correct positioning of the metanephric kidney, while the axial sonic hedgehog gene signal is critical for kidney positioning along the mediolateral axis.
4,5) The PTCH gene encodes a receptor for the protein product of the sonic hedgehog gene (SHH), a member of the hedgehog family of genes that are involved in developmental patterning during embryonic development.
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
Among fish, functional enhancers occur in introns of the immunoglobulin gene of the channel catfish [24] and the sonic hedgehog gene in ze Brafish [25].
The Sonic Hedgehog Genes Johns Hopkins University's Roger Reeves, Ph.