congenital heart defect

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Related to Heart Malformation: Congenital heart defects


existing at, and usually before, birth; referring to conditions that are present at birth, regardless of their causation. Cf. hereditary.
congenital heart defect a structural defect of the heart or great vessels or both, present at birth. Any number of defects may occur, singly or in combination. They result from improper development of the heart and blood vessels during the prenatal period. Congenital heart defects occur in about 8 to 10 of every 1000 live-born children in the United States. The most common types are tetralogy of fallot, patent ductus arteriosus, ventricular septal defect, atrial septal defect, transposition of great vessels, and coarctation of the aorta.

In many cases, depending on the severity of the defect and the physical condition of the patient, these congenital conditions can be treated by surgery. However, some are so minor that they do not significantly affect the action of the heart and do not require surgery. The cause of most of these conditions is unknown. Gene abnormalities account for about 5 per cent, and in a small number of other cases they may be seen in a child whose pregnant mother had rubella (German measles) during the first 2 or 3 months of pregnancy.


an imperfection, failure, or absence.
congenital heart defect see congenital heart defect.
aortic septal defect see aortic septal defect.
atrial septal defect see atrial septal defect.
filling defect an interruption in the contour of the inner surface of stomach or intestine revealed by radiography, indicating excess tissue or substance on or in the wall of the organ.
neural tube defect see neural tube defect.
septal defect a defect in the cardiac septum resulting in an abnormal communication between opposite chambers of the heart. Common types are aortic septal defect, atrial septal defect, and ventricular septal defect. See also congenital heart defect.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

congenital heart defect

A structural abnormality of the heart and great blood vessels that occurs during intrauterine development. Abnormalities are commonly classified by the presence or absence of cyanosis. Acyanotic abnormalities include atrial and ventricular septal defects, coarctation of the aorta, and patent ductus arteriosus. Cyanotic defects include tetralogy of Fallot, transposition of the great vessels, and hypoplastic left-sided heart syndrome.
See also: defect
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
(4) Congenital heart malformations in 50% to 60% of cases, the most common being a single atrium and a ventricular septal defect [6].
The associations between maternal gestational exposure to [PM.sub.10] and atrial septal defect, fetal patent ductus arteriosus, and overall congenital heart malformations provide further evidence that prenatal exposure to air pollution is associated with risks for fetal heart malformations.
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Patent ductus arteriosus, a commonly seen congenital heart disease, accounts for 12%~15% of congenital heart disease; 10% of cases of patent ductus arteriosus also combine other heart malformations; large patent ductus arteriosus (diameter larger than 10 mm) is more likely to induce severe pulmonary arterial hypertension.1,2 Nine patients included in this study suffered from large patent ductus arteriosus as well as multiple heart malformations and moderate or severe pulmonary arterial hypertension.
"Fever during pregnancy can be harmful to the developing embryo, with links to a significant increase in the rates of spina bifi-da and heart malformations, so small doses of paracetamol are sometimes necessary.
Yet embryos in the dark developed just the familiar slow doom of heart malformations, Incardona and his colleagues reported in 2010 in Aquatic Toxicology.
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Noninvasive and more detailed than an x-ray, a complete cardiovascular imaging and circulation evaluation are the first diagnostic procedures used to assess heart malformations. Pediatric experts Eidem, Cetta, and O'Leary from the Mayo Clinic combined 40 articles from authorities in the field to provide a comprehensive review of congenital anomalies and the use of cardiovascular ultrasound.
More than 700 babies are diagnosed each year in Lebanon with the disorder, which produces heart malformations during pregnancy, and Khalifeh said that administering treatment to those who required it was a massive task for BHF.
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The many cardiac services here range from coronary artery bypass surgery, heart valve surgery, major blood vessel diseases, and surgical correction of congenital heart malformations. Thoraric and lung surgeries can also be performed.
Is monosomy for the DiGeorge locus on chromosome 22 responsible for isolated heart malformations? Am J Hum Genet 49 (suppl): 90, 1991.