congenital heart defect

(redirected from Heart Malformation)
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Related to Heart Malformation: Congenital heart defects


existing at, and usually before, birth; referring to conditions that are present at birth, regardless of their causation. Cf. hereditary.
congenital heart defect a structural defect of the heart or great vessels or both, present at birth. Any number of defects may occur, singly or in combination. They result from improper development of the heart and blood vessels during the prenatal period. Congenital heart defects occur in about 8 to 10 of every 1000 live-born children in the United States. The most common types are tetralogy of fallot, patent ductus arteriosus, ventricular septal defect, atrial septal defect, transposition of great vessels, and coarctation of the aorta.

In many cases, depending on the severity of the defect and the physical condition of the patient, these congenital conditions can be treated by surgery. However, some are so minor that they do not significantly affect the action of the heart and do not require surgery. The cause of most of these conditions is unknown. Gene abnormalities account for about 5 per cent, and in a small number of other cases they may be seen in a child whose pregnant mother had rubella (German measles) during the first 2 or 3 months of pregnancy.


an imperfection, failure, or absence.
congenital heart defect see congenital heart defect.
aortic septal defect see aortic septal defect.
atrial septal defect see atrial septal defect.
filling defect an interruption in the contour of the inner surface of stomach or intestine revealed by radiography, indicating excess tissue or substance on or in the wall of the organ.
neural tube defect see neural tube defect.
septal defect a defect in the cardiac septum resulting in an abnormal communication between opposite chambers of the heart. Common types are aortic septal defect, atrial septal defect, and ventricular septal defect. See also congenital heart defect.

congenital heart defect

A structural abnormality of the heart and great blood vessels that occurs during intrauterine development. Abnormalities are commonly classified by the presence or absence of cyanosis. Acyanotic abnormalities include atrial and ventricular septal defects, coarctation of the aorta, and patent ductus arteriosus. Cyanotic defects include tetralogy of Fallot, transposition of the great vessels, and hypoplastic left-sided heart syndrome.
See also: defect
References in periodicals archive ?
Funds raised for Mecenat Chirurgie Cardiaque will finance the surgery in a French hospital of a child from Burkina Faso with heart malformations, as well as a one-week mission in Haiti in December 2014 to learn about local medical conditions and diagnose children with heart disease.
Many people have never heard that young children can have heart malformations.
Further analysis of the circulatory/respiratory category showed that the strongest effects were observed for the "other" subcategory (ICD-9 747-748), which excludes heart malformations (ICD-9 745-746) but includes anomalies of the aorta, patent ductus arteriosus, other anomalies of the circulatory system, and all anomalies of the respiratory system.
Malformations not recognizable at birth, especially the occurrence of heart malformations among newborns discharged earlier from the hospital, could have contributed significantly to underreporting (Gadow et al.
Endoart has been selling the FloWatch-PAB device in Europe since 2003 for newborn babies with severe heart malformations.
NASDAQ: ONCR) has acquired an exclusive license from the Children's Hospital of Philadelphia for DNA probes which can identify individuals with congenital heart malformations that are due to an inherited abnormality of chromosome 22.
The availability of these probes allows for the identification of individuals with congenital heart malformations whose offspring are at an increased risk for the same malformation.