Auris Medical announced the publication of an article that presents and discusses in detail the outcomes from the HEALOS
Phase 3 trial with AM-111, Auris Medical's investigational treatment for acute inner ear hearing loss.
Switzerland-based Auris Medical has completed patient enrolment in the Phase three HEALOS
clinical trial of its AM-111, in idiopathic sudden sensorineural hearing loss (ISSNHL), also called sudden deafness, it was reported yesterday.
Under first HEALOS
trial, which is being conducted in several European and Asian countries, the company aims to enroll approximately 255 patients with severe to profound idiopathic sudden sensorineural hearing loss.
Clinical and radiographic assessment of transforaminal lumbar interbody fusion using HEALOS
collagenhydroxyapatite sponge with autologous bone marrow aspirate.
Vitoss (B-TCP: OrthoVita, Malvern PA, USA) and Healos
(DePuy Orthopaedics, Inc.) are two of the more commonly used matrices.
(DePuy Orthopaedics, Inc, Warsaw, Ind) is a natural polymer-based product, a polymerceramic composite consisting of collagen fibers coated with hydroxyapatite and indicated for spinal fusions (195).
Fx is a moldable, injectable version of HEALOS[R] Bone Graft Replacement, which is the company's osteoconductive and osteogenic (when combined with bone marrowaspirate) bone graft substitute, shown to achieve fusion rates equivalent to autograft in peer-reviewed, published human clinical studies.
Another osteoconductive material that is sometimes mixed with aspirated cell is Healos
(DePuy Johnson and Johnson, Raynam, Mass).
Cow print, pounds 20, rainbow hottie, pounds 9, HealOs
, 020 7636 1666, www.heals.co.uk)
"The biological and structural properties of Healos
are ideal for use with GDF-5 for promoting new bone growth."
The Type C meeting had been requested by the company following the results of the HEALOS
phase 3 trial.
Auris Medical, a company that develops novel pharmaceutical therapies to protect hearing and to silence tinnitus, has enrolled the first patient into the pivotal HEALOS
clinical trial with AM-111.