HeLa culture

HeLa culture

A vigorously growing tissue culture cell line, established more than half a century ago and apparently immortal, that is used in laboratories all over the world for research and diagnostic purposes. The original cells occurred in a cervix cancer in a woman from whose name (Henrietta Lack) the term was derived. Artificial cell cultures of cancer cells achieve immortality by virtue of the enzyme TELOMERASE.
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As expected, intracellular expression of the (TTAGGG)n oligo appeared to select against malignant cells which expressed the telomeric repeat whereas HeLa cultures transfected to express a control sequence of the same length continue to thrive.