HeLa cell

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HeLa cell

(hĕl′ə)

Any of the cells of the first continuously cultured human carcinoma strain, originally obtained from cancerous cervical tissue and maintained for use in biomedical research.

HeLa cell

A line of human epithelial cells that grows well in culture. It is an immortal cancer cell that has been maintained in continuous tissue cultures for decades from a patient with carcinoma of the cervix. It is named for the first two letters of the patient's first and last names, Henrietta Lacks. HeLa cells have been used in thousands of experiments on cell growth, differentiation, and cancer, and in virology, pharmacology, and other fields.

HeLa cell

a cell type used in tissue culture that is grown as a standard in research laboratories all over the world. The culture is derived from a cervical carcinoma obtained from Henrietta Lacks in 1951.

Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

References in periodicals archive ?

The AF-MSCs and IFN[alpha]-AF-MSCs were cocultured with HeLa cells to investigate the cytopathic effect of MSCs on the cervical cancer cells.

IFN[alpha]-Expressing Amniotic Fluid-Derived Mesenchymal Stem Cells Migrate to and Suppress HeLa Cell-Derived Tumors in a Mouse Model

Regarding the cytotoxic effect of apigenin on HeLa cells, our study showed lower [IC.sub.50] values than others, with reported [IC.sub.50] values of 40 [micro]M at 30 h [39] and 37 [micro]M at 24 h [41].

Oxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer-Derived Cell Lines

MTT assay was used to estimate the cytotoxicity of the extracts to CNE-2Z, Bel-7404, and HeLa cells. Representative graphs are shown.

Cestrum nocturnum Flower Extracts Attenuate Proliferation and Induce Apoptosis in Malignant Cells through Inducing DNA Damage and Inhibiting Topoisomerase II Activity

We found a lower uptake of DAPI fluorophores into HeLa cells during the multifocus excitation compared with the single-focus excitation scheme, indicating the reduction of photo-induced cell damage in the multifocus excitation.

Photo-Induced Cell Damage Analysis for Single- and Multifocus Coherent Anti-Stokes Raman Scattering Microscopy

multiflora extract, and then the apoptotic effects of capped GNPs with medical plant extract against cervical carcinoma HeLa cells were studied.

Induction of apoptosis by green synthesized gold nanoparticles through activation of caspase-3 and 9 in human cervical cancer cells

Since we had determined that TLR4 was present in cervical tissues and could therefore mediate inflammatory signalling in the cervical mucosa, we next investigated the impact of LPS stimulation on HIV receptor expression in cervical epithelial cells, using HeLa cells as a model system.

Regulation of HIV receptor expression in cervical epithelial cells by gram-negative bacterial lipopolysaccharide

Plant extract at 200 [micro]g/mL showed virtually no effect in the cell cycle phases of HeLa cells (Figure 2A; a, b, d).

The Anticancer and Anti-inflammatory Effects of Centaurea solstitialis Extract on Human Cancer Cell Lines/Insan Kanser Hucre Hatlari Uzerinde Centaurea solstitialis Ozutunun Anti-Kanser ve Anti-Inflamatuar Etkileri

"In this study, HeLa cells are not used to reveal the process of tumorigenesis but mainly a model for addressing the underlying evolutionary forces, which need to be powerful enough to measure in laboratory settings.

Cancer Cells: No Genetic Meltdowns?

CaSki and HeLa cells were transfected with si-NEAT1 or si-NC.

Biological Function and Mechanism of Long Noncoding RNAs Nuclear-Enriched Abundant Transcript 1 in Development of Cervical Cancer

Yabe, "Human papillomavirus type 18 DNA in so-called HEP-2, KB and FL cells--further evidence that these cells are HeLa cell derivatives," Cellular and Molecular Biology, vol.

Corrigendum to "Role of Interleukin-18 in Modulation of Oral Carcinoma Cell Proliferation"

A study using green synthesis with traditional plants is the one performed by Barua et al., where Thuja occidentalis leaf extract was used to synthesize AgNPs that displayed anticancer properties against MCF-7, MDAMB-231, KB, and HeLa cell lines.

Biological Effect of Organically Coated Grias neuberthii and Persea americana Silver Nanoparticles on HeLa and MCF-7 Cancer Cell Lines

Balish, "Validation of a novel Mho microarray for a comprehensive characterisation of the Mycoplasma hominis action in HeLa cell infection," PLoS ONE, vol.

Trichomonas vaginalis Transports Virulent Mycoplasma hominis and Transmits the Infection to Human Cells after Metronidazole Treatment: A Potential Role in Bacterial Invasion of Fetal Membranes and Amniotic Fluid

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