AS reports grants from CSL Behring, HbO2
Therapeutics, LLC, Instrumentation Laboratory and Masimo Corporation, has received honoraria from CSL Behring, Masimo Corporation, Merck and Portola Pharmaceuticals, and has been a consultant for AMAG, CSL Behring, HbO2
Therapeutics, LLC, Instrumentation Laboratory, Masimo Corporation, Portola Pharmaceuticals and Vifor Pharma.
) Dwayne "The Rock" Johnson has been on "Saturday Night Live" several times.
The hemoglobin molecule in the red blood cells (RBC) serves to transport oxygen from the lungs to the tissues and binds to four oxygen atoms to form the oxygenated hemoglobin (HBO2
) molecule .
Hyperbaric oxygen (HBO2
) therapy is the medical administration of 100% oxygen (O2) at pressures higher than 1 absolute atmosphere (ATA) and during the last decade elite and competitive athletes have used HBO2
to accelerate the recovery after injuries or exercise-induced muscle damage .
Therefore, in recent years, efforts have been made to develop more and more advanced treatment strategies such as application of growth factors and cytokines , skin grafting [26, 27], and hyperbaric oxygen (HBO2
) therapy .
NIRS technique is based on two fundamental characteristics [23,24]: relative transparency of human tissue to light in the near-infrared region (700-1000 nm) and the oxygenation-dependent absorption of oxyhemoglobin and oxymyoglobin (HbO2
, MbO2) and deoxyhemoglobin and deoxymyoglobin (Hb, Mb).
They either measure the absorbance of whole blood photometrically at the isosbestic point--the wavelength in which the absorbance the two main hemoglobin derivatives, oxy-hemoglobin (HbO2
) and deoxy-hemoglobin (Hb), is the same--or, more recently, use broad spectrum photometry with multiple wavelength to get an overall picture of the absorbance spectrum, while scattered light is prevented from arriving at the sensor.
Companies Mentioned in this Report: Leucadia National Corporation, Pharmazz, Inc., NuvOx Pharma LLC, Novo A/S, Northfield Laboratories Inc., Naval Medical Research Unit of San Antonio, Health Ricerca e Sviluppo S.r.l, HbO2
Therapeutics, LLC, AstraZeneca Plc, Ambulance Victoria
Also, when passing HBo2
, So2, HB, it is reported to have a better output obtained for image reconstructing.
Photoacoustic tomography of hemoglobin: In the visible spectral range (450-600 nm), oxyhemoglobin (HbO2
) and deoxyhemoglobin (HbR) account for most of the optical absorption in blood.
Has previously reported (21) that the partial oxygen pressure values obtained by this method are significantly correlated (r=0.98) with the percentage of partial oxygen pressure (Sp[O.sub.2]) and oxyhemoglobin (HbO2
) (P < 0.0001).