Hb S


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Hb S

Abbreviation for sickle cell hemoglobin.

Hb S

Abbreviation for hemoglobin S; sickle cell hemoglobin.

Patient discussion about Hb S

Q. Please precribe for me the possible medicine (treatment) for sickle cells. Secondly, my boy lost hearing at 4 1- I need to know how sickle cells can be treated. 2- My boy just surprisingly lost his abillity to hear anything at the age of 4.

A. wow...you are going through some hard times...it's the hardest thing in the world seeing your children in pain. loosing his hearing could be caused by clots that were formed and destroyed the ear nerve. but it's unlikely it happened in both ears...so i would check it out. and about treatment- there are a variety of treatments, so i found a web site with them all. and even some that are still in research: http://www.nhlbi.nih.gov/health/dci/Diseases/Sca/SCA_Treatments.html

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References in periodicals archive ?
First-generation assay epitopes typically span amino acids 4 to 10 of the Hb [beta] chain, (7) encompassing the altered amino acid at position 6 present in Hb S and Hb C variants.
(14) For persons affected by conditions proven to shorten RBC survival such as Hb S, C, or D disease, the use of alternate tests are recommended to estimate a patient's past average glycemia.
This analysis identified a substitution at codon 6 [GAG to GTG (Glu to Val)] on one allele, corresponding to Hb S, and a substitution at codon 1 [GTG to GCG (Val to Ala)] on the other allele, corresponding to Hb Raleigh.
With alkaline agarose gel testing, some common Hb variants comigrate, such as Hb C, Hb E, Hb A2 & Hb O-Arab and Hb S, Hb D and Hb G.
SCD is diagnosed by the measurement of substantial amounts of Hb S by at least 2 separation methods, including HPLC and an electrophoretic method, such as IEF, cellulose acetate, or citrate agar.
The presence of Hb S trait produced statistically significant differences for all methods except for the D-10 and PDQ methods.
For specimens that showed chromatogram patterns consistent with sickle trait, the presence of Hb S was confirmed by use of the sodium metabisulfite reduction test (20).
Overestimation of gHb by the HA8140 ion-exchange method with samples containing Hb S trait was clinically significant only at 6% Hb [A.sub.1c].
The Hb migration order of IEF is the same as that of alkaline electrophoresis with resolution of Hb C from Hb E and Hb O and Hb S from Hb D and Hb G.
Previous studies have shown that some gHb methods yield inaccurate results with samples heterozygous for hemoglobin (Hb) C or Hb S (4-6).
Samples with hemoglobin variants were identified by comparison of retention times on the Diamat system (Bio-Rad Clinical Laboratories) to known retention times for Hb S and Hb C.