Hashimoto thyroiditis

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Ha·shi·mo·to thy·roi·di·tis

diffuse infiltration of the thyroid gland with lymphocytes, resulting in diffuse goiter, progressive destruction of the parenchyma and hypothyroidism.
Farlex Partner Medical Dictionary © Farlex 2012

Hashimoto thyroiditis

[Hakaru Hashimoto, Japanese surgeon, 1881–1934]
An autoimmune illness in which there is inflammation, followed by destruction and fibrosis of the thyroid gland, and ultimately resulting in hypothyroidism. Autoantibodies against thyroglobulin and receptors for thyroid-stimulating hormone cause the progressive destruction. Hashimoto thyroiditis is the most common cause of hypothyroidism where there are inadequate levels of iodine. It affects people of all ages but is most common in older women and in those with a family history of autoimmune diseases. Thyroid hormone replacement is required.
Synonym: chronic lymphocytic thyroiditis See: thyroid gland
Medical Dictionary, © 2009 Farlex and Partners


Hakaru, Japanese surgeon, 1881-1934.
Hashimoto disease - Synonym(s): Hashimoto thyroiditis
Hashimoto struma - Synonym(s): Hashimoto thyroiditis
Hashimoto thyroiditis - diffuse infiltration of the thyroid gland with lymphocytes. Synonym(s): autoimmune thyroiditis; Hashimoto disease; Hashimoto struma; lymphadenoid goiter; struma lymphomatosa
Medical Eponyms © Farlex 2012
References in periodicals archive ?
(2012) Fibrosing variant of Hashimoto thyroiditis is an IgG4 related disease.
A minute focus of extranodal marginal zone B-cell lymphoma arising in Hashimoto thyroiditis diagnosed with PCR after laser capture microdissection: a case report.
Given the frequent coexistence of Hashimoto thyroiditis, small cell lymphomas are more difficult to diagnose cytologically, and immunohistochemical staining or flow cytometry may be necessary to establish monoclonality and characterize surface markers.
Autoimmune thyroiditis cases also get confused with simple goitre and many Hashimoto thyroiditis patients undergo thyroidectomy.
(a) Percentage of Breg memory cells ([CD24.sup.hi] [CD38.sup.-]) in healthy donors (HD), in patients with isolated Hashimoto thyroiditis (HT), in patients with Hashimoto thyroiditis plus celiac disease (HT + CD), and in patients with celiac disease (CD).
Absence of the BRAF mutation in HBME1+ and CK19+ atypical cell clusters in Hashimoto thyroiditis: supportive evidence against preneoplastic change.
Conclusion: Vitamin-D insufficiency/deficiency has led to reduced parenchymal blood supply and increased micro-vascular resistance in Hashimoto thyroiditis patients.
Keywords: Celiac disease, children, hashimoto thyroiditis
(3) FHVT affects approximately 10 to 13% of all patients with Hashimoto thyroiditis, and it is a histologically and clinically unique entity.
Vitiligo frequently precedes the development of thyroid disease including Grave's disease and Hashimoto thyroiditis, thus screening vitiligo patients for thyroid antibody seems plausible.
Approximately 90% of the cases of hypothyroidism shown in Table 4 were attributable to Hashimoto thyroiditis, but again, for the 10% with other diagnoses the optimal management may differ.
Out of 56 cases, colloid goitre was the most common pathology in 35.7% cases, hyperplasic nodule/ toxic nodule in 25% cases, Hashimoto thyroiditis in 17.8% cases, lymphocytic thyroiditis in 17.8% cases and subacute thyroiditis (De Quervain's thyroiditis) in 3.57% cases.