haplotype

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haplotype

 [hap´lo-tīp]
1. a set of alleles of a group of closely linked genes, such as the HLA complex, which are usually inherited as a unit, an individual inheriting a complete haplotype from each parent.
2. the genetic constitution of an individual at a set of linked genes.

hap·lo·type

(hap'lō-tīp),
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. In immunogenetics, that portion of the phenotype determined by a set of closely linked genes inherited from one parent (that is, genes located on one of the pair of chromosomes).
[haplo- + G. typos, impression, model]

haplotype

(hăp′lə-tīp′)
n.
A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

hap·lo·type

(hap'lō-tīp)
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. immunogenetics That portion of the phenotype determined by a set of closely linked genes inherited from one parent (i.e., genes located on one of the pair of chromosomes). The human major histocompatability complex comprises 4 recognized loci (A, B, C, and D) for which there are more than 50 alleles. Similarly, the allotypic markers (antigens) of the immunoglobulin subclasses IgG1, IgG2, IgG3, and IgA2 occur in combinations and are inherited as units almost always unchanged in transmission; the alleles that control these various haploptypes are not linked to those controlling the antigens of the κ type L chains.
[haplo- + G. typos, impression, model]

haplotype

The entire set of allelic variants that may be found at any particular genetic location.

haplotype

see HLA SYSTEM.

Haplotype

A set of alleles (an alternative form of a gene that can occupy a particular place on a chromosome) of a group of closely linked genes which are usually inherited as a unit.
References in periodicals archive ?
Only 14 haplotypes occur commonly, say greater than 5%, in the breeds studied here.
These results, together, showed that there is a relationship between the presence of these HLA class II alleles, haplotypes, and genotypes and the risk of developing T1D in Beninese as in Caucasoid population [8].
Here we present our novel approach that will provide a simple, direct, and inexpensive approach for detecting haplotypes of unrestricted conventional PCR products from natural samples in clinical diagnosis.
So scientists want to know: Are certain centromere haplotypes transmitted more often?
Thirty-five mtDNA haplotypes were divided into two major clades: East Asian and European (except for Berkshire and part of Large White breeds).
The TCS statistical parsimony network illustrates the most parsimonious relationships between the haplotypes and the locations at which each haplotype was found (Fig.
Becky Hulme, the Wildlife Trust's red squirrel officer, said the haplotype discovery was a boost for the project.
vivax isolates that were circulating in Greece throughout the episodes of reintroduction, we displayed the haplotypes in their order of temporal appearance (Figure 3).
A set of six different haplotypes limited to the PR (pAAG, pGAC, pAGG, pAAC, pGAG, pAGC) was assayed in MCF-7 cells (Figure 1A and B) and in HEK293FT cells (Figure 1C and D).
Table 3 shows the different MAPT haplotypes in both groups.