haplotype

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haplotype

 [hap´lo-tīp]
1. a set of alleles of a group of closely linked genes, such as the HLA complex, which are usually inherited as a unit, an individual inheriting a complete haplotype from each parent.
2. the genetic constitution of an individual at a set of linked genes.

hap·lo·type

(hap'lō-tīp),
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. In immunogenetics, that portion of the phenotype determined by a set of closely linked genes inherited from one parent (that is, genes located on one of the pair of chromosomes).
[haplo- + G. typos, impression, model]

haplotype

/hap·lo·type/ (-tīp) the group of alleles of linked genes, e.g., the HLA complex, contributed by either parent; the haploid genetic constitution contributed by either parent.

haplotype

(hăp′lə-tīp′)
n.
A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

hap·lo·type

(hap'lō-tīp)
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. immunogenetics That portion of the phenotype determined by a set of closely linked genes inherited from one parent (i.e., genes located on one of the pair of chromosomes). The human major histocompatability complex comprises 4 recognized loci (A, B, C, and D) for which there are more than 50 alleles. Similarly, the allotypic markers (antigens) of the immunoglobulin subclasses IgG1, IgG2, IgG3, and IgA2 occur in combinations and are inherited as units almost always unchanged in transmission; the alleles that control these various haploptypes are not linked to those controlling the antigens of the κ type L chains.
[haplo- + G. typos, impression, model]

haplotype

The entire set of allelic variants that may be found at any particular genetic location.

haplotype

see HLA SYSTEM.

Haplotype

A set of alleles (an alternative form of a gene that can occupy a particular place on a chromosome) of a group of closely linked genes which are usually inherited as a unit.

haplotype

the group of alleles of linked genes contributed by either parent; the haploid genetic constitution contributed by either parent.
References in periodicals archive ?
A set of six different haplotypes limited to the PR (pAAG, pGAC, pAGG, pAAC, pGAG, pAGC) was assayed in MCF-7 cells (Figure 1A and B) and in HEK293FT cells (Figure 1C and D).
The remaining 2 nonnative haplotypes were found in the Blue Mountains; 1 fox with haplotype G-38 was captured at approximately 1250 m elevation upslope from Walla Walla, and the other was sampled near Baker City, Oregon, at 1120 m elevation.
17 Kawasaki originated from a single haplotype from which rapid genetic diversification into multiple sublineages occurred during global spread after the initial emergence in China in late 2014.
The survey confirmed the researchers' assumptions that the high percentage of shared haplotypes between Greek Cypriots and Turkish Cypriots is primarily of local origin, meaning that they share a common local pre-Ottoman ancestry.
The major haplotypes for all three genes of the female were always identical to that of the megalopa, whereas the major haplotypes of the male were always distinct and separated by many substitutions.
With the exception of h4, haplotypes were very similar, differing from one another at only one or two positions (Fig.
Parental haplotypes were first determined using microfluidics-based linked-read sequencing (21) on blood cell DNA obtained from the pregnant woman and her male partner.
Although both Met73Lys and Aspl21Asn mutations are required for dominant black sheep genotypes, haplotypes having only the Met73Lys mutation, H6 (AGTGT), and H7 (AGGTG), were detected in indigenous Saudi sheep expressing different coat colors.
A total of 347 mtDNA D-loop haplotypes already reported for river and swamp buffalo, 4 haplotypes for African wild buffalo and 1 haplotype for Bos indicus were also retrieved from NCBI's nucleotide databank.