HapMap


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HapMap

(hăp′măp′)
n.
A database of common genetic variants in human beings from various regions of the world, the result of an international project to describe patterns of genetic variation and their relation to various diseases.

HapMap

(hap'map)
A catalogue of human genetic variables being gathered worldwide to help increase understanding of genetic diseases and disorders.

HapMap

(hap′map″) [ hap(lotype) map]
A record of the presence of single nucleotide polymorphisms (alleles) on the chromosomes of some individuals but not others. It is used to identify the inheritance of diseases that do not follow simple mendelian genetics.
References in periodicals archive ?
On the other hand, the "C" allele frequency of rs2070744 was significantly higher than those displayed among Chinese, Japanese and other HapMap populations (for all comparisons, p=0.
Comparison with HapMap database: Results of comparison between the genotype frequencies of rs1052133 in healthy north Indian volunteers and the world population data on the HapMap database are displayed in Table III.
Results: Of the 48,905 SNPs providing results from the TMCC sample, only 45,154 could be matched with HapMap prevalence MAFs.
All known SNPs within the region were downloaded from the HapMap Phase II Genome Browser.
Cary, NC) to view the genetic ancestry compared with samples from the International HapMap Project (International HapMap Consortium 2003).
An international consortium today published a third-generation map of human genetic variation, called the HapMap, which includes data from an additional seven global populations, increasing the total number to 11 populations.
In this review, the whole-genome sequencing and HapMap studies of several important domestic animals are briefly summarized.
One produced a so-called HapMap of the maize genome, which describes the genetic differences between various strains of maize that arc currently bred around the world.
Recent international HapMap studies of genetic variation, the authors say, have revealed extended, population-specific patterns of unshuffled DNA--now called "haplotypes"--demonstrating powerful selective pressures of shockingly modern origin.
To quote from a new paper by The Bovine HapMap Consortium in Science on the launch of the Cattle Genome: "Our high resolution examination of cattle shows that unlike the dog--which has restricted diversity and high levels of inbreeding--domesticated cattle had a large ancestral population size and that more aurochs must have been domesticated than wolves; reducing the severity of the domestication bottleneck.
the HapMap Project (49) and more recently the International Cancer
The human genome sequence (1) and the HapMap project (2) for instance, have provided the resources for genome wide association (GWA) analysis and have thus led to the discovery of several potential new drug targets for therapy.