Hand Foot Syndrome

A ‘crisis’ in sickle cell anaemia caused by sludging of red cells in vessels and characterised by symmetric infarction of the small bones of the hand and foot, periosteal neo-osteogenesis, pain and swelling that may occur as early as the age of 18 months, often resolving spontaneously within 1–4 weeks
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References in periodicals archive ?
Clinical presentation n (%) Acute painful crisis 367 (49.7) Acute chest syndrome 155 (20.9) Infections 129 (17.5) Acute anemia 60 (8.1) Hand foot syndrome 14 (2.0) Stroke 10 (1.3) Priapism 4 (0.5) Table 3--Comparison of clinical presentation of the studied case by their age.
A variety of systemic as well as cutaneous side effects due to sunitinib have been described including the hand foot syndrome. We report sunitinib-induced hand foot syndrome in a 65-year-old Kashmiri male and review the literature.