Halog

halcinonide

(hal-sin-oh-nide) ,

Halog

(trade name)

Classification

Therapeutic: anti inflammatories steroidal
Pharmacologic: corticosteroids
Pregnancy Category: C

Indications

Management of inflammation and pruritis associated with various allergic and immunologic skin problems.

Action

Suppresses normal immune response and inflammation.

Therapeutic effects

Suppression of dermatologic inflammation and immune processes.

Pharmacokinetics

Absorption: Minimal. Prolonged use on large surface areas or large amounts applied or use of occlusive dressings may increase systemic absorption.
Distribution: Remains primarily at site of action.
Metabolism and Excretion: Usually metabolized in skin.
Half-life: Unknown.

Time/action profile (response depends on condition being treated)

ROUTEONSETPEAKDURATION
Topicalmin–hrshrs–dayshrs–days

Contraindications/Precautions

Contraindicated in: Hypersensitivity or known intolerance to corticosteroids or components of vehicles (ointment or cream base, preservative, alcohol); Untreated bacterial or viral infections.
Use Cautiously in: Hepatic dysfunction; Diabetes mellitus, cataracts, glaucoma, or tuberculosis (use of large amounts of high-potency agents may worsen condition); Patients with pre-existing skin atrophy; Pregnancy, lactation, or children (chronic high-dose usage may result in adrenal suppression in mother and, growth suppression in children; children may be more susceptible to adrenal and growth suppression).

Adverse Reactions/Side Effects

Dermatologic

  • allergic contact dermatitis
  • atrophy
  • burning
  • dryness
  • edema
  • folliculitis
  • hypersensitivity reactions
  • hypertrichosis
  • hypopigmentation
  • irritation
  • maceration
  • miliaria
  • perioral dermatitis
  • secondary infection
  • striae

Miscellaneous

  • adrenal suppression (use of occlusive dressings, long-term therapy)

Interactions

Drug-Drug interaction

None significant.

Route/Dosage

Topical (Adults) Apply to affected area(s) 1–3 times daily (depends on product, preparation, and condition being treated).
Topical (Children) Apply to affected area(s) once daily.

Availability

Cream: 0.025%, 0.1%
Ointment: 0.1%

Nursing implications

Nursing assessment

  • Assess affected skin before and daily during therapy. Note degree of inflammation and pruritus. Notify physician or other health care professional if symptoms of infection (increased pain, erythema, purulent exudate) develop.
  • Lab Test Considerations: Periodic adrenal function tests may be ordered to assess degree of hypothalamic-pituitary-adrenal (HPA) axis suppression in chronic topical therapy if suspected. Children and patients with dose applied to a large area, using an occlusive dressing, or using high-potency products are at highest risk for HPA suppression.
    • May cause increased serum and urine glucose concentrations if significant absorption occurs.

Potential Nursing Diagnoses

Risk for impaired skin integrity (Indications)
Risk for infection (Side Effects)
Deficient knowledge, related to medication regimen (Patient/Family Teaching)

Implementation

  • Choice of vehicle depends on site and type of lesion. Ointments are more occlusive and preferred for dry, scaly lesions. Creams should be used on oozing or intertriginous areas, where the occlusive action of ointments might cause folliculitis or maceration. Creams may be preferred for aesthetic reasons even though they may be more drying to skin than ointments. Solution is useful in hairy areas.
  • Topical: Apply ointment or cream sparingly as a thin film to clean, slightly moist skin. Wash hands immediately after application. Apply occlusive dressing only if specified by physician or other health care professional.

Patient/Family Teaching

  • Instruct patient on correct technique of medication administration. Emphasize importance of avoiding the eyes. If a dose is missed, it should be applied as soon as remembered unless almost time for the next dose.
  • Caution patient to use only as directed. Avoid using cosmetics, bandages, dressings, or other skin products over the treated area unless directed by health care professional.
  • Advise parents of pediatric patients not to apply tight-fitting diapers or plastic pants on a child treated in the diaper area; these garments work like an occlusive dressing and may cause more of the drug to be absorbed.
  • Caution women that medication should not be used extensively, in large amounts, or for protracted periods if they are pregnant or planning to become pregnant.
  • Advise patient to consult health care professional before using medicine for condition other than indicated.
  • Instruct patient to inform health care professional if symptoms of underlying disease return or worsen or if symptoms of infection develop.

Evaluation/Desired Outcomes

  • Resolution of skin inflammation, pruritus, or other dermatologic conditions.

Halog

(hăl′ŏg′)
A trademark for the drug halcinonide.
References in periodicals archive ?
"On our best estimate on when this will wrap up, our target is within this year," said LandBank Executive Vice President for Treasury and Investment Banking Sector Carel Halog.
Police Investigator John Rey Halog said officers arrived at the hotel and sealed off the area as part of the crime scene investigation.
Quezon City Police District (QCPD) Chief Supt Joselito Esquivel identified the suspect as Peter John Halog, 19, of Brgy.
Bu hynny yn destun ysgrif gan Dyfnallt: "Y noson honno yn y Traws, pan adroddwn helynt y tanio ynfyd, yr oedd golau gwyllt yn llygad Hedd Wyn; ac nid oedd neb yn fwy huawdl yn erbyn y ffieiddbeth halog oedd yn puteinio'r fro nag efe."
Algunos investigadores resaltan la complejidad en las bodegas exportadoras como respuesta a la segmentada demanda internacional de vino (Duarte Alonso, Bressan, O'Shea & Krajsic, 2014); otros en relacion con la cantidad de sistemas y subsistemas que contiene una cadena de abastecimiento (Zuluaga, 2015), o hacen referencia de los SCA en la empresa multinacional (Brady, 2015) y a la pequena, micro y mediana empresa (Nguyen, Beeton & Halog, 2014).
Halog, "Effective carbon emission reductions from using upgraded fly ash in the cement industry," Journal of Cleaner Production, vol.
Classic Chinese philosophy, such as Confucianism and Taoism, contains the fundamental idea of sustainability (Li, Cheng, Beeton, Sigler & Halog, 2015).
El mismo ano, Halog y Manik [45] utilizan una metodologia integral con un enfoque holistico en evaluacion de la sostenibilidad y formulacion de politicas para las cadenas de suministro de biocombustibles.
Cymbalta Antidepressant May cause platelet dysfunction Nexium Proton pump inhibitor Xerostomia Klor-Con Electrolyte supplement None reported Slo-Mag Supplement Vitamin D Supplement None reported Halog Corticosteroid None reported Pramipexole Anti-Parkinson's agent Xerostomia, dysphagia Ferrous sulfate Iron salt Staining with use of liquid version Vitamin B complex Vitamin None reported Soft and hard tissue examination followed by probing and recording are done at every visit.
Morris's The Life and Death of Jason, a narrative poem with inserted songs in different meters, may have influenced the structure of "The Children of Hurin" (the second version of the poem) with its insertion of Halog's song of Beren and Luthien.
Cabrera, Roberto Cedillo, Wylie Crawford, Ernesto Che Halog, Geanie Hurta.