heart failure cell

(redirected from Haemosiderin-laden macrophage)

heart fail·ure cell

macrophage in the lung during left heart failure that often carries large amounts of hemosiderin.
See also: siderophore.

heart failure cell

Any of the innumerable intra-alveolar, haemosiderin-laden macrophages in the lungs of patients with compromised cardiac function resulting in low-grade pulmonary haemorrhage (e.g., congestive heart failure). The ferrous content of heart failure cells is confirmed by an iron stain (e.g., Prussian blue).

heart fail·ure cell

(hahrt fāl'yŭr sel)
Macrophage in the lung during left heart failure that often carries large amounts of hemosiderin.
See also: siderophore

heart failure cell

A red-colored (from ingested red cells) lung macrophage often found in the sputum of patients with congestive heart failure.
See also: cell
References in periodicals archive ?
[1] Iron staining can identify haemosiderin-laden macrophages, which are a useful complementary marker.
Keywords: Haemosiderosis, Iron deficiency anaemia, Haemoptysis, Steroid, Haemosiderin-laden macrophages.
Diagnosis is suggested by the triad of haemoptysis, anaemia and pulmonary infiltrates and is secured by the finding of haemosiderin-laden macrophages (siderophages) in broncho-alveolar lavage fluid.
The gold standard for IPH diagnosis is lung biopsy but finding of haemosiderin-laden macrophages on bronchoscopy or gastric aspirate or sputum along with presence of chronic pulmonary symptoms is sufficient to diagnose the case.7
There was surrounding fat necrosis, giant cell reaction and haemosiderin-laden macrophages were prominent.
At this early stage, a sparse chronic inflammatory infiltrate, extravasated red blood cells, and haemosiderin-laden macrophages are frequently present.
KS lesions at all stages of development also frequently contain haemosiderin-laden macrophages and iron (Figure 2B).