HPX

(redirected from Haemopexin)
Also found in: Encyclopedia, Wikipedia.

HPX

A gene on chromosome 11p15.5-p15.4 that encodes haemopexin, a plasma glycoprotein and one of the so-called acute phase proteins, which binds heme with high affinity. Haemopexin transports heme from the plasma to the liver for breakdown and iron recovery, after which the free haemopexin returns to the circulation. it may be involved in protecting cells from oxidative stress.
References in periodicals archive ?
Such elements of structure as pro-domain, catalytic domain, hinge region and haemopexin domain can be identified.
The name of next domain refers to haemopexin - a haeme-binding and transporting protein.
TIMPs can be bound to metalloproteinases within catalytic and/or haemopexin domain, as shown on Figure 1.