hemoglobin A2

(redirected from Haemoglobin a2)

he·mo·glo·bin A2

[MIM*141850]
the normal Hb (Hb A2) of the formula α2Aδ2 or α2δ2, which makes up approximately 2.5% of the total adult hemoglobin concentration. At least 18 mutant variants of the δ chain have been reported.

hemoglobin A2 (Hb A2)

a normal hemoglobin present in small amounts in adults, characterized by the substitution of delta chains for beta chains. Its concentration in the blood increases in various hematologic diseases. It normally constitutes 1.5% to 3.5% of the total hemoglobin.
References in periodicals archive ?
Allocation of subjects to BTM and control group: Patients with mean corpuscular volume (MCV) <80fL, mean corpuscular haemoglobin (MCH) <27ug and Haemoglobin A2 (HbA2) [greater than or equal to]3.
It consists of two alpha polypeptide chains which pair with either two beta, gamma or delta chains to produce haemoglobin A, haemoglobin A2 and haemoglobin F, respectively.
The role of haemoglobin A2 testing in the diagnosis of thalassaemias and related haemoglobinopathies.
ICSH recommendations for the measurement of haemoglobin A2.
Haemoglobin E has the same electrophoretic mobility on alkaline cellulose acetate as haemoglobin A2 and haemoglobin C, however, the mobility of these haemoglobins differs on agar gel electrophoresis (pH 6.
Some observations on the measurement of haemoglobin A2 and S percentages by high performance liquid chromatography in the presence and absence of a thalassaemia.
Evaluation of high performance liquid chromatography for routine estimation of haemoglobin A2 and F.