CDC73

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CDC73

A gene on chromosome 1q25 that encodes a tumour suppressor involved in transcriptional and post-transcriptional control pathways, which is part of the PAF protein complex. CDC73 associates with the RNA polymerase II, subunit POLR2A, and a histone methyltransferase complex.

Molecular pathology
CDC73 mutations are associated with hyperparathyroidism (jaw tumour syndrome), familial isolated hyperparathyroidism and parathyroid carcinoma.
References in periodicals archive ?
CLASS 2: 1) Gethin Jones, Llanarmon DC, Rosi, 9; 2) Lisa Hansson, Sweden, Hyx, 13; 3) Anna Andersson, Sweden, Godis, 14; 4) Anna Andersson, Cruiaon, 15olf; 5) Elgan Jarman, Llanbrynmair, Telf Peg, 15.
The Jackson Police Department issued an alert on Twitter about the incident at 2:28 a.m., alerting the public to be on the lookout for a 2000 silver Toyota Camry with the license plate HYX 783.
Intra- and interobserver variability of both strain measurements and LVEF were examined in 10 randomly selected patients, by two investigators (CSX and HYX).