KCNE3

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KCNE3

A gene on chromosome 11q13.4 that encodes a beta subunit of the voltage-gated, isk-related potassium channel subfamily. This type-I membrane protein assembles with a potassium channel alpha-subunit to modulate gating kinetics and stabilise the multimeric complex. It is primarily expressed in the kidneys.

Molecular pathology
KCNE3 mutations are associated with hypokalemic periodic paralysis.
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