The use of these names can cause some confusion, because the name HTLV-III
was one of the names of HIV in early AIDS literature, but has since fallen out of use (11).
It was further stated that HTLV-III
proteins had been found in 85% of sera from AIDS patients and that HTLV-III
is related to HTLV-I and -II, retroviruses previously discovered by Gallo.
 "Needlestick Transmission of HTLV-III
from a Patient Infected in Africa," Lancet 2 (December 15, 1984), 1376-77; C.
Antibody seronegative human T-lymphotropic virus type III (HTLV-III
) infected patients with acquired immunodeficiency syndrome or related disorders.
Gallo and their colleagues at the National Cancer Institute in Bethesda, and Bionetics, Inc., in Kensington, Md., report that they had inadvertently used a picture of a virus grown from material provided by Montagnier's laboratory -- thus, LAV-I -- as an illustration in their initial article describing the HTLV-III
virus (SN: 4/28/84, p.
Without addressing the question of "how safe is safe," we will look at the two measures undertaken to eliminate contamination of the nation's blood supply by human immunodeficiency virus (HIV, originally called HTLV-III
): self-deferral of high-risk donors and the ELISA test to detect HIV antibody in collected units.
The Frederick group used a computer program to compare HTLV-III
proteins with proteins from EIAV; from visna virus, a lentivirus that attacks sheep; and from two leukemia viruses, bovine leukemia virus (BLV) and HTLV-I.
We also changed hepatitis assay methods for uniformity and added HTLV-III
The unusual shape change has also been reported in the nuclei of helper T lymphocytes infected by HTLV-I and -II, two leukemia-causing viruses related but not identical to the AIDS-associated virus, known variously as HTLV-III
, LAV and ARV.
Human-based plasma with analytes of human origin is generally not offered commercially because of cost, the limited supply of such analytes, and the need to use materials that are free of hepatitis and HTLV-III
, the virus that causes AIDS, consists of a whole spectrum of closely related but genetically distinct viruses, reports a team of researchers from the National Cancer Institute in Bethesda, Md., Litton Bionetics Inc.
Incubation time after HTLV-III
exposure can be as long as: