HTLV-I


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Related to HTLV-I: Human T-lymphotropic virus

HTLV-I

Abbreviation for human T-cell lymphotrophic virus type I; human lymphotropic virus, type 1.

HTLV-I

(āch′tē-ĕl′vē-wŭn′)
n.
A retrovirus associated with adult leukemia and lymphoma and with certain demyelinating diseases.

HTLV-I

abbreviation for human T-cell lymphotropic virus type I.

HTLV-I

Virology A retrovirus that immortalizes T cells; it is associated with
1. Adult T-cell lymphoma/leukemia in endemic regions of southern Japan–where up to 40% of leukemic Pts are HTLV-I-positive, and the Caribbean.
2. Chronic progressive myelopathy–tropical spastic paralysis, a condition endemic to the Caribbean, tropical Africa, and South America and.
3. HTLV-I-associated neuropathy; HTLV-I, like HIV-1, is blood-borne Carrier prevalence–US, Europe up to 0.10%; 1% of HTLV-I-infected subjects develop clinical disease, which may reflect host susceptibility and variant viral strains.

HTLV-I

Human T lymphotropic virus, type I, a virus associated with adult T cell LEUKAEMIA or T cell lymphomas and other conditions, such as tropical spastic paraparesis and POLYMYOSITIS. See also HTLV-III.
References in periodicals archive ?
34) quienes de acuerdo con sus estudios de clonacion y secuenciacion del ADN adyacente a los LTR de HTLV-I de celulas de pacientes con ATL mostraron que la region genomica flanqueante al provirus es por lo general rica en pares AT.
Since tests for distinguishing HTLV-I from HTLV-II are not routinely available, blood donors and others confirmed to be seropositive for HTLV-I/II are counseled as though they were infected with HTLV-I.
A central laboratory performed HTLV-I versus -II typing with a type-specific serologic assay, polymerase chain reaction (PCR), or both, as previously described (18).
In this sense, a homology model of HTLV-I IN was proposed and docking analysis were performed between HTLV-I IN and 3,5-DCQA, considering the magnesium ([Mg.
Integration patterns of HTLV-I provirus in relation to the clinical course of ATL: frequent clonal change at crisis from indolent disease.
A number of assertions in the patent have since been quietly forgotten, for example that there is a certain cross-reactivity with Gallo's HTLV-I and HTLV-II.
We measured the HTLV-I antibody concentrations in whole blood and plasma with the CIA method on the NAIEA-50 (Sysmex Co.
Algunos estudios iniciales conllevaron a la presuncion cientifica de que el HTLV-I era un virus proveniente del Viejo Mundo y que el HTLV--II era originario del continente americano (Hjelle et al.
In rare cases, however, HTLV-I can cause adult T-cell leukemia/lymphoma (ATL), a rare and aggressive cancer of the blood.
Editorial Note: The findings in this report indicate that false-positive ELISA reactivity for antibody to HTLV-I among blood donors in the Badger Region was associated with antecedent receipt of 1992-93 influenza virus vaccine (IVV).
At the present, the highest level of HTLV-I infection is found in southwestern Japan, where infection rates of as high as 20 to 30 percent of the general population have been reported.