HSPA9 | definition of HSPA9 by Medical dictionary
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HSPA9 A gene on chromosome 5q31.1 that encodes a member of the heat shock protein 70 (HSP70) family which localises to the mitochondria as well as the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. HSPA9 plays a role in cell proliferation, stress response and maintenance of mitochondria; it may play a role in controlling cell proliferation and ageing and act as a chaperone.
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References in periodicals archive
Conversely, PINK1 and parkin mediated mitophagy protects cells against increased susceptibility to mitochondrial stress that results from the knockdown of mitochondrial HSPA9
Heat shock proteins/chaperones-Preadipocyte proliferation has resulted in the induction of three different heat shock proteins/chaperones (HSPB1, HSPA9
Association of mortalin (HSPA9
) with liver cancer metastasis and prediction for early tumor recurrence.