HSPA8


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HSPA8

A gene on chromosome 11q24.1 that encodes a ubiquitous member of the heat shock protein 70 (HSP70) family which acts as a chaperone by binding to nascent polypeptides to facilitate correct folding. HSPA8 also acts as an ATPase in disassembling clathrin-coated vesicles during transport of membrane components through the cell. It also downregulates transcription of CITED and HSC70.
References in periodicals archive ?
Interestingly, interactions with all 6 chaperones (HSP90AB1, HSP1A/1B, HSPA13, DNAJC7, HSPA8, and STIP1) were lost in BirA*-[Txnip.
001 survival CASP1, CBR1, CRABP2, CSTB, EEF1A1, EIF6, ENO1, FLNA, GAPDH, HMGB2, HSP90AA1, HSP90AB1, HSPA8, HSPB1, ITGB4, KRT14, KRT6A, KRT8, LMNA, NDRG1, PDCD6IP, PRDX2, S100A8, S100A9, SFN, TF, TPM1, TRIM29, TUBB, TUBB3, TXN, VCL, YWHAZ Cancer ANXA2, ENO1, 11 < .
The addition of heat shack protein HSPA8 to cryapratective media improves the survival of brawn bear (Ursus 2rotus) spermatozoa during chilling and after cryapreservatian.