HSP90B | definition of HSP90B by Medical dictionary
HSP90AB1 (redirected from HSP90B)
HSP90AB1 A gene on chromosome 6p12 that encodes a constitutive HSP90 chaperone with intrinsic ATPase activity which aids proper folding of specific target proteins. HSP90AB1 promotes the maturation, structural maintenance and proper regulation of client proteins involved in cell cycle control, signal transduction, protein degradation and other processes.
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References in periodicals archive
The HSP90 protein family comprises HSP90a (HSPC1), HSP90b
(HSPC3), and gp96 (HSP4).
Heat shock proteins protect cells from excessive protein stress and subsequently from apoptosis, and we found several candidates (HSP90A, HSP90AB, and HSP90B
) to be significantly upregulated at w2 and/or w6 (Figure 5(c)).
The cytosolic partners of the AHR, Hsp90a, Hsp90b
, and AIP were identified in the AHR-TAP sample at a greater than 95% confidence.